Hypoxia-inducible factor-1 alpha in the heart: a double agent?

S Hashmi, S Al-Salam - Cardiology in review, 2012 - journals.lww.com
Hypoxia-inducible factor (HIF) is a set of transcription factors that regulate the cellular
response to hypoxia. There is a great body of evidence supporting the protective role of HIF …

Asialoerythropoietin, a nonerythropoietic derivative of erythropoietin, displays broad anti-heart failure activity

T Takeyama, G Takemura, H Kanamori… - Circulation: Heart …, 2012 - Am Heart Assoc
Background—We investigated the effects of asialoerythropoietin (asialoEPO), a
nonerythrogenic erythropoietin derivative, on 3 murine models of heart failure with different …

[HTML][HTML] Did clinical trials in which erythropoietin failed to reduce acute myocardial infarct size miss a narrow therapeutic window?

MI Talan, I Ahmet, EG Lakatta - PLoS One, 2012 - journals.plos.org
Background To test a hypothesis that in negative clinical trials of erythropoietin in patients
with acute myocardial infarction (MI) the erythropoietin (rhEPO) could be administered …

Evaluation of the effect of one large dose of erythropoietin against cardiac and cerebral ischemic injury occurring during cardiac surgery with cardiopulmonary bypass …

M Joyeux‐Faure, M Durand, D Bedague… - Fundamental & …, 2012 - Wiley Online Library
Cardiac surgery and cardiopulmonary bypass (CPB) induce ischemia–reperfusion and
subsequent cellular injury with inflammatory reaction. Clinical and experimental studies …

[HTML][HTML] Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat

M Teixeira, P Rodrigues-Santos, P Garrido… - Journal of Pharmacy …, 2012 - journals.lww.com
Objective: Recombinant human erythropoietin (rhEPO) therapy under circumstances of
moderate chronic renal failure (CRF), with yet lower kidney and heart lesion, may have a …

[HTML][HTML] Effects of erythropoietin on electrocardiogram changes in carbon monoxide poisoning: an experimental study in rats

MA Rezaee, SA Moallem, M Imenshahidi… - Iranian Journal of …, 2012 - ncbi.nlm.nih.gov
The aim of this study was to define the electrocardiogram (ECG) changes following the
moderate to severe CO intoxication in rats, and also evaluating the effect of erythropoietin …

The influence of EPO and hypothermia on the kidneys of rats after perinatal asphyxia

V Stojanović, N Vučković, S Spasojević, N Barišić… - Pediatric …, 2012 - Springer
The aim of this study was to determine the effects of erythropoietin (EPO), moderate
hypothermia, and a combination thereof on the kidneys of newborn rats damaged during …

The influence of EPO and hypothermia on the kidneys of rats after perinatal asphyxia

V Stojanovic, N Vuckovic, S Spasojevic, N Barisic… - Pediatric …, 2012 - go.gale.com
The aim of this study was to determine the effects of erythropoietin (EPO), moderate
hypothermia, and a combination thereof on the kidneys of newborn rats damaged during …

An increase in endogenous erythropoietin concentrations has no cardioprotective effects in patients undergoing coronary artery bypass graft surgery

M Momeni, G Liistro, P Baele, A Matta, D Kahn… - … of Cardiothoracic and …, 2012 - Elsevier
OBJECTIVE: Preliminary data showed an increase in endogenous erythropoietin (EPO)
concentrations after acute normovolemic hemodilution (ANH) in patients undergoing …

Эффекты эритропоэтина в клинике и эксперименте

ЕА Лебедева, АД Беляевский… - Фундаментальные …, 2012 - elibrary.ru
Учитывая то обстоятельство, что организм–саморегулирующаяся система, новым
направлением в терапии критических состояний представляется использование …