Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages
T Kodama, H Hikita, T Kawaguchi… - Cell Death & …, 2012 - nature.com
Anti-apoptotic Bcl-2 family proteins, which inhibit the mitochondrial pathway of apoptosis,
are involved in the survival of various hematopoietic lineages and are often dysregulated in …
are involved in the survival of various hematopoietic lineages and are often dysregulated in …
Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic …
One mechanism for disrupting the MLL gene in myelodysplastic syndrome (MDS) and acute
myeloid leukemia (AML) is through partial tandem duplication (MLL-PTD); however, the …
myeloid leukemia (AML) is through partial tandem duplication (MLL-PTD); however, the …
Involvement of thrombopoietin in acinar cell necrosis in L-arginine-induced acute pancreatitis in mice
J Shen, R Wan, G Hu, F Wang, J Shen, X Wang - Cytokine, 2012 - Elsevier
Thrombopoietin (TPO) plays an important role in injuries of different tissues. However, the
role of TPO in acute pancreatitis (AP) is not yet known. The aim of the study was to …
role of TPO in acute pancreatitis (AP) is not yet known. The aim of the study was to …
Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis of human malignant cancer cells
MY Li, N Ci Liang, GG Chen - Current drug targets, 2012 - ingentaconnect.com
Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F) is a chemical compound isolated from
Pteris semipinnata L (PsL), a Chinese traditional herb. 5F has been known to exert antitumor …
Pteris semipinnata L (PsL), a Chinese traditional herb. 5F has been known to exert antitumor …
Treatment with alpha7-selective ligands
M Bencherif, MB Marrero - EP Patent App. 11,075,209 A, 2012 - Google Patents
EP2409703A1 - Treatment with alpha7-selective ligands - Google Patents EP2409703A1 -
Treatment with alpha7-selective ligands - Google Patents Treatment with alpha7-selective …
Treatment with alpha7-selective ligands - Google Patents Treatment with alpha7-selective …
[图书][B] Investigation of activated tyrosine kinases in myeloproliferative neoplasms
MR Marit - 2012 - search.proquest.com
Myeloproliferative neoplasms (MPNs) are a group of disorders characterized by an excess
production of a specific, fully functional blood cell type. Many cases involve deregulation of a …
production of a specific, fully functional blood cell type. Many cases involve deregulation of a …
巨核球造血とアポトーシス
上妻行則 - 日本血栓止血学会誌, 2012 - jstage.jst.go.jp
増加し, 胞体突起形成巨核球の platelet bud 及び血小板においても Bcl-xL タンパクの発現は確認
されること, また抗血小板抗体を投与した血小板減少モデルマウスにおいても, 血小板回復期に至る …
されること, また抗血小板抗体を投与した血小板減少モデルマウスにおいても, 血小板回復期に至る …