Antiviral agents and HIV prevention: controversies, conflicts, and consensus
Antiviral agents can be used to prevent HIV transmission before exposure as preexposure
prophylaxis (PrEP), after exposure as postexposure prophylaxis, and as treatment of …
prophylaxis (PrEP), after exposure as postexposure prophylaxis, and as treatment of …
HIV treatment as prevention: the utility and limitations of ecological observation
Results from several observational studies of HIV-discordant couples and a randomized
controlled trial (HIV Prevention Trials Network 052) show that antiretroviral therapy (ART) …
controlled trial (HIV Prevention Trials Network 052) show that antiretroviral therapy (ART) …
Formulation, pharmacokinetics and pharmacodynamics of topical microbicides
JL Adams, ADM Kashuba - Best practice & research Clinical obstetrics & …, 2012 - Elsevier
The development of safe topical microbicides that effectively prevent human
immunodeficiency virus (HIV) infection is a major goal in curbing the human …
immunodeficiency virus (HIV) infection is a major goal in curbing the human …
HIV prevention by oral preexposure prophylaxis
W Heneine, A Kashuba - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The impressive advances in antiretroviral (ARV) therapy of chronic human
immunodeficiency virus (HIV) infections during the last decade and the availability of potent …
immunodeficiency virus (HIV) infections during the last decade and the availability of potent …
Pharmacokinetic modelling of efavirenz, atazanavir, lamivudine and tenofovir in the female genital tract of HIV-infected pre-menopausal women
Background and Objectives A previously published study of antiretroviral pharmacokinetics
in the female genital tract of HIV-infected women demonstrated differing degrees of female …
in the female genital tract of HIV-infected women demonstrated differing degrees of female …
Single-and multiple-dose pharmacokinetics of darunavir plus ritonavir and etravirine in semen and rectal tissue of HIV-negative men
KC Brown, KB Patterson, SH Jennings… - JAIDS Journal of …, 2012 - journals.lww.com
Background: Antiretroviral therapy has become a central component of combination in HIV
prevention efforts. Defining the individual exposure of commercially available antiretroviral …
prevention efforts. Defining the individual exposure of commercially available antiretroviral …
Potential use of protease inhibitors as vaginal and colorectal microbicides
C Herrera, RJ Shattock - Current HIV research, 2012 - ingentaconnect.com
The new generation of microbicide candidates is based on the use of antiretroviral (ARV)
drugs. The first compounds tested were selected among ARV classes that block the early …
drugs. The first compounds tested were selected among ARV classes that block the early …
[图书][B] Pushing the envelope: Enhancing the potency of D-peptide HIV entry inhibitors by membrane localization
JN Francis - 2012 - search.proquest.com
Thirty four million people are infected with HIV, the causative agent of acquired
immunodeficiency syndrome (AIDS), which has caused an estimated 25 million deaths in …
immunodeficiency syndrome (AIDS), which has caused an estimated 25 million deaths in …
[图书][B] The evaluation of candidate microbicide antiretrovirals against wild type and drug resistant HIV-1 in vitro
SM Schader - 2012 - search.proquest.com
Over the last 30 years, the human immunodeficiency virus (HIV)/acquired immunodeficiency
syndrome (AIDS) mêlée has endured despite valiant efforts made by the research …
syndrome (AIDS) mêlée has endured despite valiant efforts made by the research …