FOXO transcription factors throughout T cell biology
SM Hedrick, RH Michelini, AL Doedens… - Nature Reviews …, 2012 - nature.com
The outcome of an infection with any given pathogen varies according to the dosage and
route of infection, but, in addition, the physiological state of the host can determine the …
route of infection, but, in addition, the physiological state of the host can determine the …
Aging and dry eye disease
J Ding, DA Sullivan - Experimental gerontology, 2012 - Elsevier
Dry eye disease is a prevalent eye disorder that in particular affects the elderly population.
One of the major causes of dry eye, meibomian gland dysfunction (MGD), shows increased …
One of the major causes of dry eye, meibomian gland dysfunction (MGD), shows increased …
Upregulation of MircoRNA-370 induces proliferation in human prostate cancer cells by downregulating the transcription factor FOXO1
Z Wu, H Sun, W Zeng, J He, X Mao - 2012 - journals.plos.org
Forkhead box protein O1 (FOXO1), a key member of the FOXO family of transcription factors,
acts as a tumor suppressor and has been associated with various key cellular functions …
acts as a tumor suppressor and has been associated with various key cellular functions …
Chlorogenic acid induces apoptotic cell death in U937 leukemia cells through caspase-and mitochondria-dependent pathways
JS Yang, CW Liu, YS Ma, SW Weng, NY Tang, SH Wu… - In Vivo, 2012 - iv.iiarjournals.org
Chlorogenic acid exists widely in edible and medicinal plants and acts as an antioxidant. It is
known to exert antitumor activity via induction of apoptosis in many human cancer cells …
known to exert antitumor activity via induction of apoptosis in many human cancer cells …
Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice
The present study was to explore the biological responses of the newly compound, MJ-29 in
murine myelomonocytic leukemia WEHI-3 cells in vitro and in vivo fates. We focused on the …
murine myelomonocytic leukemia WEHI-3 cells in vitro and in vivo fates. We focused on the …
Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase-and mitochondria-dependent pathways
FS Chueh, YT Hsiao, SJ Chang, PP Wu… - Oncology …, 2012 - spandidos-publications.com
Leukemia, one of the causes of cancer-related death in humans, is an aggressive
malignancy via the rapid growth of abnormal white blood cells. The aim of this study was to …
malignancy via the rapid growth of abnormal white blood cells. The aim of this study was to …
Opposite regulation of vitamin D receptor by ATRA in AML cells susceptible and resistant to vitamin D-induced differentiation
Some leukemic cell lines can be driven to differentiate to monocyte-like cells by 1, 25-
dihydroxyvitamin D3 (1, 25D) and to granulocyte-like cells by all-trans retinoic acid (ATRA) …
dihydroxyvitamin D3 (1, 25D) and to granulocyte-like cells by all-trans retinoic acid (ATRA) …
Foxo3a: an integrator of immune dysfunction during HIV infection
J Van Grevenynghe, RA Cubas, S DaFonseca… - Cytokine & growth factor …, 2012 - Elsevier
Chronic HIV infection, which is primarily characterized by the progressive depletion of total
CD4+ T cells, also causes persistent inflammation and immune activation. This is followed …
CD4+ T cells, also causes persistent inflammation and immune activation. This is followed …
CRABP‐II‐and FABP5‐independent all‐trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells
NN Chen, Y Li, ML Wu, ZL Liu, YS Fu… - Experimental …, 2012 - Wiley Online Library
The effect of all‐trans retinoic acid (ATRA) on cutaneous squamous cell carcinomas (c‐
SCC) has been poorly described. Because the imbalance of CRABP‐II‐mediated anticancer …
SCC) has been poorly described. Because the imbalance of CRABP‐II‐mediated anticancer …
Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis
C Giampietri, S Petrungaro, F Padula, A D'Alessio… - Apoptosis, 2012 - Springer
TNF-alpha levels in prostate cancer correlate with the extent of disease and are significantly
elevated in the metastatic stage. TNF receptor superfamily controls two distinct signalling …
elevated in the metastatic stage. TNF receptor superfamily controls two distinct signalling …