Calcium channels and pumps in cancer: changes and consequences
Increases in intracellular free Ca 2+ play a major role in many cellular processes. The
deregulation of Ca 2+ signaling is a feature of a variety of diseases, and modulators of Ca …
deregulation of Ca 2+ signaling is a feature of a variety of diseases, and modulators of Ca …
Diagnostic and prognostic molecular biomarkers for prostate cancer
G Kristiansen - Histopathology, 2012 - Wiley Online Library
Kristiansen G (2012) Histopathology 60, 125–141 Diagnostic and prognostic molecular
biomarkers for prostate cancer Prostate cancer is the most common malignant tumour in …
biomarkers for prostate cancer Prostate cancer is the most common malignant tumour in …
Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines
Y Okamoto, T Ohkubo, T Ikebe… - … journal of oncology, 2012 - spandidos-publications.com
Several members of the transient receptor potential (TRP)-channel family are expressed in
cancer cells. One, cold/menthol-sensitive TRPM8, is reportedly an important player in …
cancer cells. One, cold/menthol-sensitive TRPM8, is reportedly an important player in …
Regulation of TRPM8 channel activity
Transient Receptor Potential Melastatin 8 (TRPM8) is a Ca2+ permeable non-selective
cation channel directly activated by cold temperatures and chemical agonists such as …
cation channel directly activated by cold temperatures and chemical agonists such as …
Menthol inhibits the proliferation and motility of prostate cancer DU145 cells
Y Wang, X Wang, Z Yang, G Zhu, D Chen… - Pathology & Oncology …, 2012 - Springer
In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has
emerged as a promising prognostic marker and putative therapeutic target in prostate …
emerged as a promising prognostic marker and putative therapeutic target in prostate …
V‐ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast …
Lysosomal trafficking and protease exocytosis in osteoclasts are essential for ruffled border
formation and bone resorption. Yet the mechanism underlying lysosomal trafficking and the …
formation and bone resorption. Yet the mechanism underlying lysosomal trafficking and the …
CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway
MR Tang, YX Wang, S Guo, SY Han, D Wang - Apoptosis, 2012 - Springer
In this work, we studied the effects of CUB and Sushi multiple domains 1 gene (CSMD1)
expression in A375 melanoma cells in vivo and in vitro. CSDM1 expression decreased …
expression in A375 melanoma cells in vivo and in vitro. CSDM1 expression decreased …
TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde
B Oehler, A Scholze, M Schaefer, K Hill - … -Schmiedeberg's archives of …, 2012 - Springer
Melanoma is the most dangerous form of skin cancer occurring in Caucasians with rising
incidence. They are remarkably resistant to conventional anti-tumour therapies like …
incidence. They are remarkably resistant to conventional anti-tumour therapies like …
[HTML][HTML] Involvement of transient receptor potential melastatin 7 channels in sophorae radix-induced apoptosis in cancer cells: Sophorae radix and TRPM7
BJ Kim - Journal of Pharmacopuncture, 2012 - ncbi.nlm.nih.gov
Sophorae Radix (SR) plays a role in a number of physiologic and pharmacologic functions
in many organs. Objective: The aim of this study was to clarify the potential role for transient …
in many organs. Objective: The aim of this study was to clarify the potential role for transient …
Effect of surgical castration on expression of TRPM8 in urogenital tract of male rats
Z Yang, X Wang, G Zhu, Z Zhou, Y Wang, D Chen… - Molecular biology …, 2012 - Springer
Trpm8 (melastatin-related transient receptor potential member 8), a member of the transient
receptor potential (TRP) superfamily, encoding a cation channel named TRPM8, has been …
receptor potential (TRP) superfamily, encoding a cation channel named TRPM8, has been …