Baculovirus production for gene therapy: the role of cell density, multiplicity of infection...

JC Drugmand, YJ Schneider, SN Agathos - Biotechnology advances, 2012 - Elsevier

Insect cells (IC) and particularly lepidopteran cells are an attractive alternative to mammalian
cells for biomanufacturing. Insect cell culture, coupled with the lytic expression capacity of …

被引用次数：156 相关文章所有 12 个版本

[PDF] springer.com

Live attenuated influenza viruses produced in a suspension process with avian AGE1. CR. pIX cells

V Lohr, Y Genzel, I Jordan, D Katinger, S Mahr… - BMC …, 2012 - Springer

Background Current influenza vaccines are trivalent or quadrivalent inactivated split or
subunit vaccines administered intramuscularly, or live attenuated influenza vaccines (LAIV) …

被引用次数：51 相关文章所有 18 个版本

Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants

B Isken, Y Genzel, U Reichl - Vaccine, 2012 - Elsevier

In cell culture-based influenza vaccine production significant efforts are directed towards
virus seed optimization for maximum yields. Typically, high growth reassortants (HGR) …

被引用次数：33 相关文章所有 10 个版本

[PDF] researchgate.net

Production of insecticidal baculoviruses in insect cell cultures: potential and limitations

JD Claus, VV Gioria, GA Micheloud… - … —Basic and Other …, 2012 - books.google.com

The potential of baculoviruses to be employed as insecticides is known since more than 75
years ago (Benz, 1986). To date, over 30 different baculoviruses are used to control several …

被引用次数：17 相关文章所有 5 个版本

An Insight into the Physiology of Insect Cells: The Role of Energetic Metabolism on the Cell Density Effect

V Bernal, N Carinhas, F Monteiro, R Ambrósio… - Proceedings of the 21st …, 2012 - Springer

In the last years, the Baculovirus Expression Vector System (BEVS) has gained increasing
interest for its many biotechnologically relevant applications, ranging from single proteins to …