Background Regular use of aspirin after a diagnosis of colon cancer has been associated
with a superior clinical outcome. Experimental evidence suggests that inhibition of …

There has been an increasing role for molecular diagnostics in the diagnosis and
management of cancer, and colorectal carcinoma is no exception. Recent molecular …

Background Epidermal growth factor receptor gene copy number (EGFR GCN) has been
heavily investigated as a potential predictive biomarker for the treatment of metastatic …

Background To investigate the frequency and relationship of the KRAS, BRAF and PIK3CA
mutations and the loss of PTEN expression in Chinese patients with colorectal cancer …

Phosphoinositide 3-kinases (PI3Ks) and their phosphatidylinositol 3, 4, 5-triphosphate
(PIP3) products regulate a variety of cellular processes. Of these, PI3Kα is an attractive …

Background Given the high incidence of metastatic esophageal squamous cell carcinoma,
especially in Asia, we screened for the presence of somatic mutations using OncoMap …

Abstract Background Role of KRAS, BRAF and PIK3CA mutations in pathogenesis of
colorectal cancer (CRC) has been recently investigated worldwide. In this population-based …

This consensus statement, conceived as a joint initiative of the Spanish Society of Pathology
and the Spanish Society of Medical Oncology, makes diagnostic and treatment …

Este documento de consenso nace como una iniciativa conjunta de la Sociedad Española
de Anatomía Patológica (SEAP) y de la Sociedad Española de Oncología Médica (SEOM) y …

In the drama John Gabriel Borkman Ibsen attributes great importance to sounds. The
contrast between presence and absence of sounds, other sound effects and especially the …