The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities

S Nattel, D Dobrev - European heart journal, 2012 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …

Novel molecular targets for atrial fibrillation therapy

D Dobrev, L Carlsson, S Nattel - Nature reviews Drug discovery, 2012 - nature.com
Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for
substantial morbidity and mortality in the general population. Current treatments have …

New pharmacological approaches to atrial fibrillation

JT Milnes, DJ Madge, JW Ford - Drug discovery today, 2012 - Elsevier
Atrial fibrillation (AF) is the most common cardiac arrhythmia facing physicians, afflicting
13% of men and 11% of women over 85 years of age. Epidemiological studies estimate that …

Proarrhythmic atrial calcium cycling in the diseased heart

N Voigt, S Nattel, D Dobrev - Calcium Signaling, 2012 - Springer
During the last decades Ca 2+ has been found to play a crucial role in cardiac arrhythmias
associated with heart failure and a number of congenital arrhythmia syndromes. Recent …

离子通道与心房颤动发生的研究进展

付勇, 刘慧, 于风旭, 廖斌 - 临床心血管病杂志, 2012 - cqvip.com
离子通道与心房颤动发生的研究进展-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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Low-level ganglionated plexus stimulation facilitates atrial fibrillation: in vivo and in vitro studies

L Wu, Z Lu, H Jiang, B He, W He, B Cui, X Hu… - Autonomic …, 2012 - Elsevier
OBJECTVES: The purpose of the present study was to investigate whether long term low
level autonomic activation can form electrophysiological substrate for atrial fibrillation (AF) …