Myeloproliferative neoplasms (MPNs) are the most common cause of Budd-Chiari syndrome
(BCS) and nonmalignant, noncirrhotic portal vein thrombosis (PVT). In this meta-analysis …

Disease overview: Polycythemia vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms primarily characterized by erythrocytosis and thrombocytosis …

Objective To share our decades of experience with primary myelofibrosis and underscore
the importance of outcomes research studies in designing clinical trials and interpreting their …

SF3B1 mutations were recently reported in myelodysplastic syndromes (MDSs), especially
in the presence of ring sideroblasts (RSs). We sought to define the interaction between …

Among spliceosome component mutations, those involving SF3B1 are most frequent in
myelodysplastic syndromes with ring sideroblasts (MDS-RS;∼ 75% incidence) and SRSF2 …

Myeloid malignant diseases comprise chronic (including myelodysplastic syndromes,
myeloproliferative neoplasms and chronic myelomonocytic leukemia) and acute (acute …

Isocitrate dehydrogenase (IDH) mutations are frequent in blast-phase myeloproliferative
neoplasms and might therefore contribute to leukemic transformation. We examined this …

Unlike the case with acute myeloid leukemia, there is limited information on the prognostic
impact of isocitrate dehydrogenase (IDH) mutations in myelodysplastic syndromes (MDS). In …

Researchers have successfully applied exome sequencing to discover causal variants in
selected individuals with familial, highly penetrant disorders. We demonstrate the utility of …

The guideline group regarding the diagnosis and management of myelofibrosis was
selected to be representative of UK‐based medical experts, together with a contribution from …