Multi-modal multi-task learning for joint prediction of multiple regression and classification variables in Alzheimer's disease

D Zhang, D Shen… - NeuroImage, 2012 - Elsevier
Many machine learning and pattern classification methods have been applied to the
diagnosis of Alzheimer's disease (AD) and its prodromal stage, ie, mild cognitive impairment …

Effects of multicomponent exercise on cognitive function in older adults with amnestic mild cognitive impairment: a randomized controlled trial

T Suzuki, H Shimada, H Makizako, T Doi, D Yoshida… - BMC neurology, 2012 - Springer
Background To examine the effects of a multicomponent exercise program on the cognitive
function of older adults with amnestic mild cognitive impairment (aMCI). Methods Design …

Sparse learning and stability selection for predicting MCI to AD conversion using baseline ADNI data

J Ye, M Farnum, E Yang, R Verbeeck, V Lobanov… - BMC neurology, 2012 - Springer
Abstract Background Patients with Mild Cognitive Impairment (MCI) are at high risk of
progression to Alzheimer's dementia. Identifying MCI individuals with high likelihood of …

Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI

S Vos, I van Rossum, L Burns, D Knol, P Scheltens… - Neurobiology of …, 2012 - Elsevier
Our aim was to identify the best diagnostic test sequence for predicting Alzheimer's disease
(AD)-type dementia in subjects with mild cognitive impairment (MCI) using cerebrospinal …

Magnetic resonance imaging based clinical research in Alzheimer's disease

N Fayed, PJ Modrego, GR Salinas… - Journal of Alzheimer's …, 2012 - content.iospress.com
Alzheimer's disease (AD) is the most common cause of dementia in elderly people in
western countries. However important goals are unmet in the issue of early diagnosis and …

Is radiological evaluation as good as computer-based volumetry to assess hippocampal atrophy in Alzheimer's disease?

C Boutet, M Chupin, O Colliot, M Sarazin, G Mutlu… - Neuroradiology, 2012 - Springer
Introduction Hippocampus volumetry is a useful surrogate marker for the diagnosis of
Alzheimer's disease (AD). Our purpose was to compare visual assessment of medial …

[PDF][PDF] DTI and structural MRI classification in Alzheimer's disease

L Mesrob, M Sarazin, V Hahn-Barma… - Advances in molecular …, 2012 - file.scirp.org
In this paper, we propose a fully automated method to individually classify patients with
Alzheimer's disease (AD) and elderly control subjects based on diffusion tensor (DTI) and …

Apolipoprotein E ɛ2 and functional decline in amnestic mild cognitive impairment and Alzheimer disease

A Bonner-Jackson, O Okonkwo, G Tremont… - The American journal of …, 2012 - Elsevier
Background Recent work has demonstrated the potentially protective effects of the
apolipoprotein E (APOE) ɛ2 allele on cognitive functioning in individuals at risk for …

Combining structural brain changes improves the prediction of Alzheimer's disease and mild cognitive impairment

N Zhang, X Song, Y Zhang - Dementia and geriatric cognitive disorders, 2012 - karger.com
Background: Several structural brain changes have been associated with Alzheimer's
disease (AD). This study investigated the prediction of AD by combining multiple brain …

Neurochemical alterations of the entorhinal cortex in amnestic mild cognitive impairment (aMCI): a three-year follow-up study

SW Seo, JH Lee, SM Jang, ST Kim, J Chin… - Archives of Gerontology …, 2012 - Elsevier
The neurochemical alterations in the entorhinal cortex have not yet been measured, even
though the entorhinal cortex is the earliest involved brain region in aMCI. In this study, we …