Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …

Lissencephaly is a disorder of neuronal migration resulting in abnormal cerebral cortical
sulcation and gyration. Affected children present with microcephaly, developmental delay …

Microdeletions encompassing the MAPT (Tau) locus resulting in intellectual disability raised
the hypothesis that Tau may regulate early functions in the developing brain. Our results …

Neurological disorders characterized by abnormal neuronal migration, organization, axon
guidance, and maintenance have recently been associated with missense and splice‐site …

Malformations of the midbrain (MB) and hindbrain (HB) have become topics of considerable
interest in the neurology and neuroscience literature in recent years. The combined …

The spectrum of lissencephaly ranges from absent (agyria) or decreased (pachygyria)
convolutions to less severe malformation known as subcortical band heterotopia. Mutations …

During cortical development, proliferating neural progenitors exhibit polarized apical and
basolateral membranes that are maintained by tightly controlled and membrane‐specific …

The similarities between brain tumor stem cells and neural stem cells suggest a possible
stem cell origin of tumorigenesis. Recently, cells with features of stem cells have been …

The importance of the microtubule cytoskeleton during in utero brain development has
emerged from a body of functional and genetic studies and was recently strengthened by the …

Periventricular heterotopia (PH), clumps of neurons mislocated beside the ventricle, is
caused by failure to initiate migration during embryogenesis. We report on a 32‐month‐old …