Aims: In addition to nitric oxide and carbon monoxide, hydrogen sulfide (H2S) is an
endogenously synthesized gaseous molecule that acts as an important signaling molecule …

Tumour recurrence frequently occurs after radiotherapy, but the characteristics,
intratumoural localization and post-irradiation behaviour of radioresistant cancer cells …

Non-invasive optical imaging techniques, such as fluorescence imaging (FI) or
bioluminescence imaging (BLI) have emerged as important tools in biomedical research. As …

Within the ischemic penumbra, blood flow is sufficiently reduced that it results in hypoxia
severe enough to arrest physiological function. Nevertheless, it has been shown that cells …

Purpose. We aimed to clearly visualize heterogeneous distribution of hypoxia-inducible
factor 1α (HIF) activity in tumor tissues in vivo. Methods. We synthesized of 125 I-IPOS, a 125 …

在体光学分子影像作为一种快速发展的生物医学影像技术, 以其实时, 定量及非侵入性等特点,
已被广泛应用于各学科的研究中. 光学分子影像技术在监测乳腺癌的远处转移 …

Tumor oxygenation is increasingly recognized as an important factor to enhance the efficacy
of chemo-and radiotherapy. MRI is becoming a widely accepted diagnostic imaging modality …

Brain metastasis represents a poor prognosis and is frequently the cause of death in breast
cancer patients. Tumor microcirculation and oxygenation play important roles in malignant …

Purpose. We aimed to clearly visualize heterogeneous distribution of hypoxia-inducible
factor 1α (HIF) activity in tumor tissues in vivo. Methods. We synthesized of 125I-IPOS, a 125I …

Hypoxic regions in solid tumors are critically important in tumor physiology and cancer
treatment, and they appear to be strongly associated with malignant progression and …