Stress can be defined as a brain–body reaction towards stimuli arising from the environment
or from internal cues that are interpreted as a disruption of homeostasis. The organization of …

Leptin, an adipocytokine produced in the peripheral system as well as in the brain, is
implicated in obesity, food intake, glucose homeostasis, and energy expenditure. Leptin …

Level of adiposity is linked to dementia in epidemiological studies. Overweight and obesity
in mid-and late-life may increase risk for dementia, whereas decline in body weight or body …

The blood–brain barrier (BBB) regulates the blood‐to‐brain passage of gastrointestinal
hormones, thus informing the brain about feeding and nutritional status. Disruption of this …

Level of adiposity is linked to manifest dementia and Alzheimer's disease in epidemiological
studies. Overweight and obesity in mid-and late-life may increase risk for dementia, whereas …

The hormone leptin, secreted predominantly from adipose tissue, plays a crucial role in the
regulation of numerous neuroendocrine functions, from energy homeostasis to reproduction …

The incidence of AD is increasing in parallel with the increase in life expectancy. At the
same time the prevalence of metabolic syndrome and obesity is reaching epidemic …

It is well established that the hormone leptin circulates in the plasma in amounts proportional
to body fat content and it regulates food intake and body weight via its actions in the …

HIV-associated neurocognitive disorders (HAND) remain prevalent even with widespread
use of combination antiretroviral therapy (ART), suggesting a potential role for co-morbidities …

BACKGROUND: We have shown that high mid-life central adiposity may increase the risk for
dementia after 32 years. Leptin, an adipose tissue hormone, is correlated with adiposity …