Asthma outcomes: biomarkers

SJ Szefler, S Wenzel, R Brown, SC Erzurum… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Measurement of biomarkers has been incorporated within clinical research
studies of asthma to characterize the population and associate the disease with …

[HTML][HTML] Airway disease: similarities and differences between asthma, COPD and bronchiectasis

R Athanazio - Clinics, 2012 - SciELO Brasil
Airway diseases are highly prevalent worldwide; however, the prevalence of these diseases
is underestimated. Although these diseases present several common characteristics, they …

Omalizumab modulates bronchial reticular basement membrane thickness and eosinophil infiltration in severe persistent allergic asthma patients

AM Riccio, RW Dal Negro… - International journal …, 2012 - journals.sagepub.com
Severe persistent asthma causes a substantial morbidity and mortality burden and is
frequently not well controlled, despite intensive guideline-based therapy. The unique …

Obesity is associated with increased asthma severity and exacerbations, and increased serum immunoglobulin E in inner‐city adults

S Fitzpatrick, R Joks… - Clinical & Experimental …, 2012 - Wiley Online Library
Background Obesity is associated with increased asthma and atopy. Objective To determine
whether or not obesity in inner‐city adults is associated with increased asthma prevalence …

The effect of single and multiple infections on atopy and wheezing in children

NM Alcantara-Neves, RV Veiga, VCC Dattoli… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: The current epidemic of asthma and atopy has been explained by
alterations in immune responses related to reduction in childhood infections. However, the …

Omalizumab in patients with severe asthma: the XCLUSIVE study

C Schumann, C Kropf, T Wibmer… - The clinical …, 2012 - Wiley Online Library
Abstract Background and Aims: Although the efficacy and safety of omalizumab (OMA) in
uncontrolled severe allergic asthma has been demonstrated in several randomised …

μ-Chain–deficient mice possess B-1 cells and produce IgG and IgE, but not IgA, following systemic sensitization and inhalational challenge in a fungal asthma model

S Ghosh, SA Hoselton, JM Schuh - The Journal of Immunology, 2012 - journals.aai.org
Allergic bronchopulmonary aspergillosis is often difficult to treat and results in morbidity
associated with chronic airway changes. This study assessed the requirement for B cells …

Onset of mucosal, dermal, and general symptoms in relation to biomarkers and exposures in the dwelling: a cohort study from 1992 to 2002

B Sahlberg, D Norbäck, G Wieslander, T Gislason… - Indoor …, 2012 - Wiley Online Library
We examined the associations between biomarkers of allergy and inflammation, indoor
environment in dwellings, and incidence and remission of symptoms included in the sick …

Relationships between total and allergen-specific serum IgE concentrations and lung function in young adults

C Rajendra, E Zoratti, S Havstad, C Nicholas… - Annals of Allergy …, 2012 - Elsevier
BACKGROUND: Prior studies have shown relationships between serum immunoglobulin E
(IgE) and asthma. OBJECTIVE: To investigate relationships between total and allergen …

[PDF][PDF] Asthma in adults; epidemiology, risk factor and patterns of presentation: a cross sectional, questionnaire based study in Baghdad Teaching

SM Muhammed, KM Sultan, MY Abdulrazaq - Kerbala Journal of Medicine, 2012 - iasj.net
Method: Two hundred twenty five asthmatic patients diagnosed by questionnaire, supported
by clinical detection of wheeze, were included in a cross sectional study done in outpatients …