Transcriptional control of effector and memory CD8+ T cell differentiation
During an infection, T cells can differentiate into multiple types of effector and memory T
cells, which help to mediate pathogen clearance and provide long-term protective immunity …
cells, which help to mediate pathogen clearance and provide long-term protective immunity …
Homeostatic maintenance of T cells and natural killer cells
Homeostasis in the immune system encompasses the mechanisms governing maintenance
of a functional and diverse pool of lymphocytes, thus guaranteeing immunity to pathogens …
of a functional and diverse pool of lymphocytes, thus guaranteeing immunity to pathogens …
Regulating the immune system via IL-15 transpresentation
EF Castillo, KS Schluns - Cytokine, 2012 - Elsevier
Transpresentation has emerged as an important mechanism mediating IL-15 responses in a
subset of lymphocytes during the steady state. In transpresentation, cell surface IL-15, bound …
subset of lymphocytes during the steady state. In transpresentation, cell surface IL-15, bound …
CD8 T cell memory: it takes all kinds
SE Hamilton, SC Jameson - Frontiers in immunology, 2012 - frontiersin.org
Understanding the mechanisms that regulate the differentiation and maintenance of CD8+
memory T cells is fundamental to the development of effective T cell-based vaccines …
memory T cells is fundamental to the development of effective T cell-based vaccines …
Uncovering the primary CD4+ T cell immune response to HIV-1 and Vaccinia virus.
CML Munier - 2012 - unsworks.unsw.edu.au
Ex-vivo T cell responses to vaccines and viral antigens are not always detectable by
conventional functional T cell assays such as lymphoproliferation, IFN-γ ELIspot and …
conventional functional T cell assays such as lymphoproliferation, IFN-γ ELIspot and …
[图书][B] The role of β2 integrins in host responses to bacterial infection and T cell development
TO Bose - 2012 - search.proquest.com
Integrins are heterodimeric adhesion molecules that play an important role in cell-to-cell, as
well as cell-to-endothelium interactions in the immune system. The members of the (β2 …
well as cell-to-endothelium interactions in the immune system. The members of the (β2 …
The transcriptional regulation of CD8⁺ T cells during acute infection
JA Best - 2012 - escholarship.org
CD8⁺ T cells posses the dual function of specifically targeting and killing host cells
harboring intracellular pathogens, while at the same time maintaining the ability to" …
harboring intracellular pathogens, while at the same time maintaining the ability to" …