Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides
Heparin and HS (heparan sulfate) exert their wide range of biological activities by interacting
with extracellular protein ligands. Among these important protein ligands are various …
with extracellular protein ligands. Among these important protein ligands are various …
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β
J Lin, X Qin, Z Zhu, J Mu, L Zhu, K Wu, H Jiao, X Xu… - IUBMB …, 2012 - Wiley Online Library
Four and a half LIM domain (FHL) proteins belong to a family of LIM‐only proteins that have
been implicated in the development and progression of various types of cancers. However …
been implicated in the development and progression of various types of cancers. However …
Nanoantibodies for detection and blocking of bioactivity of human vascular endothelial growth factor a165
SV Tillib, TI Ivanova, EY Lyssuk, SS Larin… - Biochemistry …, 2012 - Springer
Nanoantibodies (single-domain antibodies, nanobodies) derived from noncanonical single-
chain immunoglobulins provide an attractive tool for in vitro and in vivo diagnostics as well …
chain immunoglobulins provide an attractive tool for in vitro and in vivo diagnostics as well …
A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton
J Zhang, J Zhou, X Ren, Y Diao, H Li, H Jiang… - Investigational new …, 2012 - Springer
Receptor tyrosine kinases (RTKs) modulate a variety of cellular events, including cell
proliferation, differentiation, mobility and apoptosis. In addition, RTKs have been validated …
proliferation, differentiation, mobility and apoptosis. In addition, RTKs have been validated …
miRNAs, a potential target in the treatment of Non-Small-Cell Lung Carcinomas
M Malleter, C Jacquot, B Rousseau, C Tomasoni… - Gene, 2012 - Elsevier
Lung cancer is a serious public health problem and Non Small Cell Lung Carcinoma,
NSCLC, is particularly resistant to current treatments. So it is important to find new strategies …
NSCLC, is particularly resistant to current treatments. So it is important to find new strategies …
Expression and significance of vascular endothelial growth factor C from multiple specimen sources in esophageal squamous cell carcinoma
Background Esophageal squamous cell carcinoma (ESCC) is a common malignancy with a
very poor prognosis. Vascular endothelial growth factor C (VEGF-C) plays an important role …
very poor prognosis. Vascular endothelial growth factor C (VEGF-C) plays an important role …
Наноантитела для детекции и блокирования биологической активности фактора роста эндотелия сосудов А165 человека
СВ Тиллиб, ТИ Иванова, ЕЮ Лысюк, СС Ларин… - Биохимия, 2012 - elibrary.ru
Наноантитела (однодоменные антитела, nanobodies®), являющиеся производными
неканонических одноцепочечных иммуноглобулинов, представляют собой …
неканонических одноцепочечных иммуноглобулинов, представляют собой …
Recent progress and related patents on the applications of SULF1/SULF2 enzymes in regenerative medicine and cancer therapies
GK Dhoot - Recent Patents on Regenerative Medicine, 2012 - ingentaconnect.com
SULF1/SULF2, the two extracellular sulfatase enzymes, edit the sulfation patterns of
heparan sulfate proteoglycans (HSPGs) enabling them to modulate the activities of growth …
heparan sulfate proteoglycans (HSPGs) enabling them to modulate the activities of growth …
An overview of antibody-based cancer therapy
QF Miao, RG Shao, YS Zhen - Yao xue xue bao= Acta …, 2012 - europepmc.org
The use of monoclonal antibodies (mAbs) for cancer therapy has achieved considerable
success in recent years. Approximate 17 monoclonal antibodies have been approved as …
success in recent years. Approximate 17 monoclonal antibodies have been approved as …