Osteoarthritis of the knee causes pain, limits activity, and impairs quality of life. Although it
cannot be cured, advances in understanding and treatment have improved the outlook for …

Background Osteoarthritis is a chronic joint disease that involves degeneration of articular
cartilage. Pre‐clinical data suggest that doxycycline might act as a disease‐modifying agent …

The increasing prevalence of painful knee osteoarthritis has created an additional demand
for pharmacologic management to prevent or delay surgical management …

Aims Cryoballoon (CB) ablation has proven very effective in achieving pulmonary vein
isolation (PVI). The Achieve catheter (AC) is a novel inner lumen catheter designed to be …

Sports participation is associated with an increased risk of future osteoarthritis (OA), much of
which results from joint injury. No strong evidence exists that moderate sporting activity in …

The latest in a series of meta-analyses of trials assessing viscosupplementation for knee
osteoarthritis is the first to raise concerns about its safety. Questions remain, however …

OBJECTIVE: The high tibial osteotomy (HTO) is an effective strategy for treatment of painful
medial compartment knee osteoarthritis. Effects on cartilage quality are largely unknown …

Osteoarthritis (OA) is a leading cause of disability in middle‐aged and older adults with the
prevalence expected to increase by 40% by 2025. This dramatic projected increase in OA …

Zusammenfassung Evidenzbasierte Medizin (EbM) fordert, dass bei klinischen
Entscheidungen das weltweit beste verfügbare Wissen berücksichtigt wird, um eine …

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