Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

TW Robbins, CM Gillan, DG Smith, S de Wit… - Trends in cognitive …, 2012 - cell.com
A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual
of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we …

[HTML][HTML] Dopamine, serotonin and impulsivity

JW Dalley, JP Roiser - Neuroscience, 2012 - Elsevier
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD

DA Fair, D Bathula, MA Nikolas… - Proceedings of the …, 2012 - National Acad Sciences
Research and clinical investigations in psychiatry largely rely on the de facto assumption
that the diagnostic categories identified in the Diagnostic and Statistical Manual (DSM) …

[HTML][HTML] Reaction time variability in ADHD: a review

L Tamm, ME Narad, TN Antonini, KM O'brien… - …, 2012 - Elsevier
For the past decade, intra-individual variability in reaction times on computerized tasks has
become a central focus of cognitive research on Attention-Deficit/Hyperactivity Disorder …

[HTML][HTML] Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

GS Dichter, CA Damiano, JA Allen - Journal of neurodevelopmental …, 2012 - Springer
This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

[HTML][HTML] Basal ganglia beta oscillations accompany cue utilization

DK Leventhal, GJ Gage, R Schmidt, JR Pettibone… - Neuron, 2012 - cell.com
Beta oscillations in cortical-basal ganglia (BG) circuits have been implicated in normal
movement suppression and motor impairment in Parkinson's disease. To dissect the …

[HTML][HTML] The relationship between impulsive choice and impulsive action: a cross-species translational study

N Broos, L Schmaal, J Wiskerke, L Kostelijk, T Lam… - PloS one, 2012 - journals.plos.org
Maladaptive impulsivity is a core symptom in various psychiatric disorders. However, there is
only limited evidence available on whether different measures of impulsivity represent …

Developmental context and treatment principles for ADHD among college students

AP Fleming, RJ McMahon - Clinical child and family psychology review, 2012 - Springer
Attention-deficit/hyperactivity disorder (ADHD) affects between 2 and 8% of college students.
ADHD is associated with impaired academic, psychological, and social functioning, and with …

[HTML][HTML] Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats

PJJ Baarendse, LJMJ Vanderschuren - Psychopharmacology, 2012 - Springer
Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as
ADHD, mania, personality disorders and drug addiction. The effectiveness of drugs targeting …

Orbitofrontal reward sensitivity and impulsivity in adult attention deficit hyperactivity disorder

G Wilbertz, LT van Elst, MR Delgado, S Maier, B Feige… - Neuroimage, 2012 - Elsevier
Impulsivity symptoms of adult attention deficit hyperactivity disorder (ADHD) such as
increased risk taking have been linked with impaired reward processing. Previous studies …