Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

T Vilsbøll, M Christensen, AE Junker, FK Knop… - Bmj, 2012 - bmj.com
Objective To determine whether treatment with agonists of glucagon-like peptide-1 receptor
(GLP-1R) result in weight loss in overweight or obese patients with or without type 2 …

Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions

M Snel, JT Jonker, J Schoones, H Lamb… - International journal …, 2012 - Wiley Online Library
The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage.
Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM). Not the …

Body mass index and risk of incident hypertension over the life course: the Johns Hopkins Precursors Study

HM Shihab, LA Meoni, AY Chu, NY Wang, DE Ford… - Circulation, 2012 - Am Heart Assoc
Background—The obesity-hypertension link over the life course has not been well
characterized, although the prevalence of obesity and hypertension is increasing in the …

Obesity and appetite control

K Suzuki, CN Jayasena… - Journal of Diabetes …, 2012 - Wiley Online Library
Obesity is one of the major challenges to human health worldwide; however, there are
currently no effective pharmacological interventions for obesity. Recent studies have …

The obesity epidemic and its impact on hypertension

T Nguyen, DCW Lau - Canadian Journal of Cardiology, 2012 - Elsevier
Global obesity rates have increased steadily in both developed and emerging countries over
the past several decades with little signs of slowing down. Over 1.5 billion people worldwide …

Body fatness and markers of thyroid function among US men and women

CM Kitahara, EA Platz, PW Ladenson, AM Mondul… - PloS one, 2012 - journals.plos.org
Background We evaluated the association of central versus overall adiposity on levels of
thyroid stimulating hormone (TSH), free triiodothyronine (fT3), and free thyroxine (fT4) …

The comparison of a technology‐based system and an in‐person behavioral weight loss intervention

CA Pellegrini, SD Verba, AD Otto, DL Helsel… - …, 2012 - Wiley Online Library
The purpose of this study was to compare a technology‐based system, an in‐person
behavioral weight loss intervention, and a combination of both over a 6‐month period in …

Parental feeding practices and socioeconomic status are associated with child adiposity in a multi-ethnic sample of children

M Cardel, AL Willig, A Dulin-Keita, K Casazza… - Appetite, 2012 - Elsevier
Parental feeding practices have been associated with children's weight status, but results
have been inconsistent across populations. Research is needed to elucidate the …

Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations

LS Szczepaniak, RG Victor, R Mathur… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE To evaluate racial/ethnic differences in pancreatic triglyceride (TG) levels and
their relationship to β-cell dysfunction in humans. RESEARCH DESIGN AND METHODS We …

[HTML][HTML] Plain-water intake and risk of type 2 diabetes in young and middle-aged women

A Pan, VS Malik, MB Schulze, JAE Manson… - The American journal of …, 2012 - Elsevier
Background: The replacement of caloric beverages such as sugar-sweetened beverages
(SSBs) and fruit juices with noncaloric beverages such as plain water has been …