Liposomal antibiotics for the treatment of infectious diseases

M Alhariri, A Azghani, A Omri - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Liposomal delivery systems have been utilized in developing effective
therapeutics against cancer and targeting microorganisms in and out of host cells and within …

Lipases, liposomes and lipid-prodrugs

A Arouri, AH Hansen, TE Rasmussen… - Current opinion in colloid …, 2013 - Elsevier
Colloidal and interfacial phenomena lie at the core of drug formulation, drug delivery, as well
as drug binding and action at diseased sites, eg, in cancer therapy. We review a class of …

Tunable complement activation by particles with variable size and Fc density

PM Pacheco, B LE, D White, T Sulchek - Nano Life, 2013 - World Scientific
The complement system is an integral innate immune component that is made up of a
cascade of enzymatic proteins that, once activated, results in lysis of invading pathogens …

Renal retention of lipid microbubbles: a potential mechanism for flank discomfort during ultrasound contrast administration

YN Liu, J Khangura, A Xie, JT Belcik, Y Qi… - Journal of the American …, 2013 - Elsevier
Background The etiology of flank pain sometimes experienced during the administration of
ultrasound contrast agents is unknown. The aim of this study was to investigate whether …

Expedition of liposomes to intracellular targets in solid tumors after intravenous administration

S Malhi, K Dixit, H Sohi, R Shegokar - Journal of Pharmaceutical …, 2013 - Springer
Liposomes as a drug delivery system provides a leading approach for the systemic
(intravenous) administration of drugs. Several approaches to kill tumor cells specifically …

Bidirectional interaction between nanoparticles and cells of the mononuclear phagocytic system

WP Caron, S Rawal, G Song, P Kumar… - Handbook of …, 2013 - World Scientific
Nanoparticle (NP) uptake by the mononuclear phagocytic system (MPS) has been described
through several in vitro and in vivo studies, and is a field of research that is constantly …

Mechanisms and barriers to RNAi delivery

J Zhou, JJ Rossi - … delivery and therapeutic applications of RNAi, 2013 - Wiley Online Library
RNA interference (RNAi) is an evolutionarily conserved, endogenous process for post‐
transcriptional regulation of gene expression. By taking advantage of the cell's RNAi …

Biocompatibility of hemoglobin vesicles, a cellular-type artificial oxygen carrier, on blood cells and plasma proteins in vitro and in vivo

H Azuma, M Fujihara, H Sakai - … -Based Oxygen Carriers as Red Cell …, 2013 - Springer
Abstract Hemoglobin vesicles (HbV), cellular-type artificial oxygen carriers, are human
hemoglobin encapsulated within a phospholipid bilayer membrane. Because HbV are …

[HTML][HTML] Complement activation-related pseudoallergy in dogs following intravenous administration of a liposomal formulation of meglumine antimoniate

RR Ribeiro, EP Moura, WM Sampaio… - Pesquisa Veterinária …, 2013 - SciELO Brasil
The increasing use of nanotechnologies in advanced therapies has allowed the observation
of specific adverse reactions related to nanostructures. The toxicity of a novel liposome …

[引用][C] 粒径与表面电荷影响脂质体体内药物靶向递送的研究进展

杨艳芳, 谢向阳, 杨阳, 张慧, 梅兴国 - 药学学报, 2013