Computational and theoretical methods for protein folding
M Compiani, E Capriotti - Biochemistry, 2013 - ACS Publications
A computational approach is essential whenever the complexity of the process under study
is such that direct theoretical or experimental approaches are not viable. This is the case for …
is such that direct theoretical or experimental approaches are not viable. This is the case for …
C-terminal turn stability determines assembly differences between Aβ40 and Aβ42
R Roychaudhuri, M Yang, A Deshpande… - Journal of molecular …, 2013 - Elsevier
Oligomerization of the amyloid β-protein (Aβ) is a seminal event in Alzheimer's disease.
Aβ42, which is only two amino acids longer than Aβ40, is particularly pathogenic. Why this is …
Aβ42, which is only two amino acids longer than Aβ40, is particularly pathogenic. Why this is …
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation
We report the effects of the interaction of two camelid antibody fragments, generally called
nanobodies, namely cAb-HuL5 and a stabilized and more aggregation-resistant variant cAb …
nanobodies, namely cAb-HuL5 and a stabilized and more aggregation-resistant variant cAb …
Elements of coevolution in biological sequences
O Rivoire - Physical review letters, 2013 - APS
Studies of coevolution of amino acids within and between proteins have revealed two types
of coevolving units: coevolving contacts, which are pairs of amino acids distant along the …
of coevolving units: coevolving contacts, which are pairs of amino acids distant along the …
Detecting repetitions and periodicities in proteins by tiling the structural space
The notion of energy landscapes provides conceptual tools for understanding the
complexities of protein folding and function. Energy landscape theory indicates that it is …
complexities of protein folding and function. Energy landscape theory indicates that it is …
Mutational effects on the folding dynamics of a minimized hairpin
M Scian, I Shu, KA Olsen, K Hassam, NH Andersen - Biochemistry, 2013 - ACS Publications
The fold stabilities and folding dynamics of a series of mutants of a model hairpin, KTW-
NPATGK-WTE (HP7), are reported. The parent system and the corresponding DPATGK loop …
NPATGK-WTE (HP7), are reported. The parent system and the corresponding DPATGK loop …
Structural role of exons in hemoglobin
M Piwowar, M Banach, L Konieczny… - Bio-Algorithms and …, 2013 - degruyter.com
The role of exons can be studied on many levels, one of which pertains to protein structure. It
is a well-known fact that secondary structural motifs do not directly correspond to exons …
is a well-known fact that secondary structural motifs do not directly correspond to exons …
Structural role of exons in hemoglobin
M Banach, I Roterman, M Piwowar… - Bio-Algorithms and …, 2013 - bamsjournal.com
The role of exons can be studied on many levels, one of which pertains to protein structure. It
is a wellknown fact that secondary structural motifs do not directly correspond to exons …
is a wellknown fact that secondary structural motifs do not directly correspond to exons …
High-Pressure NMR Spectroscopy of Proteins
L Ballard, J Jonas - … Systems Under Extreme Conditions: Structure and …, 2013 - Springer
Advanced high-resolution NMR spectroscopy, including 2D NMR techniques, combined with
the high-pressure capability represents a powerful new tool in studies of proteins. Selected …
the high-pressure capability represents a powerful new tool in studies of proteins. Selected …