5‐HT radioligands for human brain imaging with PET and SPECT

LM Paterson, BR Kornum, DJ Nutt… - Medicinal research …, 2013 - Wiley Online Library
The serotonergic system plays a key modulatory role in the brain and is the target for many
drug treatments for brain disorders either through reuptake blockade or via interactions at …

Systematic review, structural analysis, and new theoretical perspectives on the role of serotonin and associated genes in the etiology of psychopathy and sociopathy

BO Yildirim, JJL Derksen - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Since its theoretical inception, psychopathy has been considered by philosophers,
clinicians, theorists, and empirical researchers to be substantially and critically explained by …

CNS distribution of metabotropic glutamate 2 and 3 receptors: transgenic mice and [3H] LY459477 autoradiography

RA Wright, BG Johnson, C Zhang, C Salhoff… - …, 2013 - Elsevier
Group II metabotropic glutamate (mGlu) receptor agonists were efficacious in randomized
clinical research trials for schizophrenia and generalized anxiety disorder. The regional …

Regulating Prefrontal Cortex Activation: An Emerging Role for the 5-HT2A Serotonin Receptor in the Modulation of Emotion-Based Actions?

S Aznar, AB Klein - Molecular neurobiology, 2013 - Springer
The prefrontal cortex (PFC) is involved in mediating important higher-order cognitive
processes such as decision making, prompting thereby our actions. At the same time, PFC …

[HTML][HTML] Comodulation of dopamine and serotonin on prefrontal cortical rhythms: a theoretical study

DH Wang, KF Wong-Lin - Frontiers in Integrative Neuroscience, 2013 - frontiersin.org
The prefrontal cortex (PFC) is implicated to play an important role in cognitive control.
Abnormal PFC activities and rhythms have been observed in some neurological and …

[HTML][HTML] Systemic inflammation alters central 5-HT function as determined by pharmacological MRI

Y Couch, CJ Martin, C Howarth, J Raley… - Neuroimage, 2013 - Elsevier
Considerable evidence indicates a link between systemic inflammation and central 5-HT
function. This study used pharmacological magnetic resonance imaging (phMRI) to study …

Involvement of serotonin 5-HT3 receptors in the modulation of noradrenergic transmission by serotonin reuptake inhibitors: a microdialysis study in rat brain

B Fernández-Pastor, JE Ortega, JJ Meana - Psychopharmacology, 2013 - Springer
Rationale Selective serotonin reuptake inhibitors (SSRIs), in addition to being able to
enhance serotonergic neurotransmission, are able to modulate other brain systems involved …

Direct comparison of [18F]MH.MZ and [18F]altanserin for 5‐HT2A receptor imaging with PET

HD Hansen, A Ettrup, MM Herth, A Dyssegaard… - Synapse, 2013 - Wiley Online Library
Imaging the cerebral serotonin 2A (5‐HT2A) receptors with positron emission tomography
(PET) has been carried out in humans with [11C] MDL 100907 and [18F] altanserin …

Suitability of [18F]Altanserin and PET to Determine 5-HT2A Receptor Availability in the Rat Brain: In Vivo and In Vitro Validation of Invasive and Non-Invasive …

T Kroll, D Elmenhorst, A Matusch, F Wedekind… - Molecular imaging and …, 2013 - Springer
Purpose While the selective 5-hydroxytryptamine type 2a receptor (5-HT 2A R) radiotracer
[18 F] altanserin is well established in humans, the present study evaluated its suitability for …

[PDF][PDF] La tomographie d'émission monophotonique chez le petit animal: application à l'imagerie des récepteurs sérotoninergiques centraux

N Dumas - 2013 - academia.edu
Le cerveau humain est probablement l'un des objets les plus fascinants qui soient si l'on
considère la complexité des interactions cellulaires qui le caractérise. Il est pour l'essentiel …