The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar
disorder (BD), a severe mental illness arising from complex interactions between genes and …

Global warming is causing changes in temperature rapidly for over two decades. The
increased temperature during reproductive phase of plant growth has emerged as a serious …

The eukaryotic cell depends on multitiered homeostatic systems ensuring maintenance of
proteostasis, organellar integrity, function and turnover, and overall cellular viability. At the …

The general natures of protein dynamics and thermodynamics are analyzed on the basis of
irreversible theory for protein folding and protein thermodynamic structure theory. Main …

Genevestigator analysis has indicated heat shock induction of transcripts for NADPH-
thioredoxin reductase, type C (NTRC) in the light. Here we show overexpression of NTRC in …

The heat-shock response in cells, involving increased transcription of a specific set of genes
in response to a sudden increase in temperature, is a highly conserved biological response …

Arsenic (As) is a toxic metalloid existing widely in the environment, and chronic exposure to
it through contaminated drinking water has become a global problem of public health. The …

The mechanism whereby the prototypical chaperonin GroEL performs work on substrate
proteins has not yet been fully elucidated, hindered by lack of detailed structural and …

The invasive Pomacea canaliculata estivates during periods of drought and should cope
with harmful effects of reoxygenation during arousal. We studied thiobarbituric acid reactive …

Type I chaperonins are large oligomeric protein ensembles that are involved in the folding
and assembly of other proteins. Chloroplast chaperonins and co-chaperonins exist in …