[HTML][HTML] Pathology and pathogenesis of vascular cognitive impairment—a critical update
KA Jellinger - Frontiers in aging neuroscience, 2013 - frontiersin.org
Vascular cognitive impairment (VCI)[vascular cognitive disorder (VCD), vascular dementia]
describes a continuum of cognitive disorders ranging from mild cognitive impairment (MCI) …
describes a continuum of cognitive disorders ranging from mild cognitive impairment (MCI) …
[HTML][HTML] Amyloid PET in clinical practice: its place in the multidimensional space of Alzheimer's disease
Amyloid imaging is currently introduced to the market for clinical use. We will review the
evidence demonstrating that the different amyloid PET ligands that are currently available …
evidence demonstrating that the different amyloid PET ligands that are currently available …
Impact of molecular imaging on the diagnostic process in a memory clinic
R Ossenkoppele, ND Prins, YAL Pijnenburg… - Alzheimer's & …, 2013 - Elsevier
BACKGROUND:[11C] Pittsburgh compound B ([11C] PIB) and [18F]-2-fluoro-2-deoxy-D-
glucose ([18F] FDG) PET measure fibrillar amyloid-β load and glucose metabolism …
glucose ([18F] FDG) PET measure fibrillar amyloid-β load and glucose metabolism …
Pathogenesis of cerebral microbleeds: in vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment
Objective Cerebral microbleeds (CMBs) are a neuroimaging marker of small vessel disease
(SVD) with relevance for understanding disease mechanisms in cerebrovascular disease …
(SVD) with relevance for understanding disease mechanisms in cerebrovascular disease …
The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction
NL Marchant, BR Reed, N Sanossian… - JAMA …, 2013 - jamanetwork.com
Importance β-Amyloid (Aβ) deposition and vascular brain injury (VBI) frequently co-occur
and are both associated with cognitive decline in aging. Determining whether a direct …
and are both associated with cognitive decline in aging. Determining whether a direct …
[HTML][HTML] Associations between white matter hyperintensities and β amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor …
The goal of this study was to assess the relationship between Aβ deposition and white
matter pathology (ie, white matter hyperintensities, WMH) on microstructural integrity of the …
matter pathology (ie, white matter hyperintensities, WMH) on microstructural integrity of the …
Amyloid deposition in early onset versus late onset Alzheimer's disease
Background: Patients with early-onset Alzheimer's disease (EOAD) may differ from those
with late-onset Alzheimer's disease (LOAD) in cognitive impairment profiles and clinical …
with late-onset Alzheimer's disease (LOAD) in cognitive impairment profiles and clinical …
The effects of small vessel disease and amyloid burden on neuropsychiatric symptoms: a study among patients with subcortical vascular cognitive impairments
Neuropsychiatric symptoms (NPS) affect the quality of life of patients with dementia and
increase the burden on caregivers. We aimed to evaluate how small vessel disease (SVD) …
increase the burden on caregivers. We aimed to evaluate how small vessel disease (SVD) …
[HTML][HTML] 18F-florbetaben Aβ imaging in mild cognitive impairment
K Ong, VL Villemagne, A Bahar-Fuchs, F Lamb… - Alzheimer's Research & …, 2013 - Springer
Introduction 18 F-florbetaben and positron emission tomography were used to examine the
relationships between β-amyloid (Aβ) deposition, cognition, hippocampal volume, and white …
relationships between β-amyloid (Aβ) deposition, cognition, hippocampal volume, and white …
Cognitive deficits of pure subcortical vascular dementia vs Alzheimer disease: PiB-PET–based study
Objectives: Despite many neuropsychological studies to differentiate subcortical vascular
dementia (SVaD) from Alzheimer disease (AD), previous studies did not eliminate …
dementia (SVaD) from Alzheimer disease (AD), previous studies did not eliminate …