Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …

Chronic disease is a major social challenge of the twenty-first century. In this review, we
examine the evidence for discordance between modern diets and those on which …

Objective: To identify the emotional and motivational processes that reinstate palatable food
intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to …

Obesity is characterized as an excess accumulation of body fat resulting from a positive
energy balance. It is the major risk factor for type 2 diabetes (T2D). The evidence for familial …

The size of an infant at birth, a measure of gestational growth, has been recognized for many
years as a biomarker of future risk of morbidity. Both being born small for gestational age …

Specific methylation of appetite-related genes in leukocytes could serve as a useful
biomarker to predict weight regain after an energy restriction program. We aimed to evaluate …

The pathophysiology of obesity is extremely complex and is associated with extensive gene
expression changes in tissues throughout the body. This situation, combined with the fact …

The development of diet-induced obesity (DIO) can potently alter multiple aspects of
dopamine signaling, including dopamine transporter (DAT) expression and dopamine …

Objective To test whether high‐fat diet (HFD) decreases dopaminergic tone in reward
regions of the brain and evaluate whether these changes reverse after removal of the HFD …

INTRODUCTION: Dopamine is one among several neurotransmitters that regulate food
intake and overeating. Thus, it has been linked to the pathophysiology of obesity and high …