Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists

F Cattaneo, M Parisi, R Ammendola - International journal of molecular …, 2013 - mdpi.com
The formyl peptide receptor 2 (FPR2) is a remarkably versatile transmembrane protein
belonging to the G-protein coupled receptor (GPCR) family. FPR2 is activated by an array of …

CGRP and migraine: could PACAP play a role too?

EA Kaiser, AF Russo - Neuropeptides, 2013 - Elsevier
Migraine is a debilitating neurological disorder that affects about 12% of the population. In
the past decade, the role of the neuropeptide calcitonin gene-related peptide (CGRP) in …

Targeted drug delivery to treat pain and cerebral hypoxia

PT Ronaldson, TP Davis - Pharmacological reviews, 2013 - ASPET
Limited drug penetration is an obstacle that is often encountered in treatment of central
nervous system (CNS) diseases including pain and cerebral hypoxia. Over the past several …

Neuropeptides and hippocampal neurogenesis

MJ Zaben, WP Gray - Neuropeptides, 2013 - Elsevier
Hippocampal neurogenesis is important for modulating the behavioural responses to stress
and for certain forms of learning and memory. The mechanisms underlying the necessary …

[PDF][PDF] Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP‐PKA pathway

H Ji, Y Zhang, X Shen, F Gao, CY Huang, C Abad… - …, 2013 - Wiley Online Library
Hepatic ischemia and reperfusion injury (IRI), an exogenous antigen‐independent local
inflammation response, occurs in multiple clinical settings, including liver transplantation …

[HTML][HTML] Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA

P Niewiadomski, A Zhujiang, M Youssef, JA Waschek - Cellular signalling, 2013 - Elsevier
Sonic hedgehog (Shh) signaling is essential for proliferation of cerebellar granule cell
progenitors (cGCPs) and its aberrant activation causes a cerebellar cancer …

[HTML][HTML] Vasoactive intestinal peptide inhaled agonists: potential role in respiratory therapeutics

AG Mathioudakis, V Chatzimavridou-Grigoriadou… - Hippokratia, 2013 - ncbi.nlm.nih.gov
Abstract Purpose of review: Vasoactive Intestinal Peptide (VIP) is a neuropeptide, expressed
by lymphoid as well as neural cells, which has diverse effects on the cellular mediators of …

Behavioral phenotypes in schizophrenic animal models with multiple combinations of genetic and environmental factors

H Hida, A Mouri, Y Noda - Journal of pharmacological sciences, 2013 - jstage.jst.go.jp
Schizophrenia is a multifactorial psychiatric disorder in which both genetic and
environmental factors play a role. Genetic [eg, Disrupted-in-schizophrenia 1 (DISC1) …

Characterisation of a transcriptome to find sequence differences between two differentially migrating subspecies of the willow warbler Phylloscopus trochilus

M Lundberg, J Boss, B Canbäck, M Liedvogel… - Bmc Genomics, 2013 - Springer
Background Animal migration requires adaptations in morphological, physiological and
behavioural traits. Several of these traits have been shown to possess a strong heritable …

Antiproliferative effects of PACAP and VIP in serum-starved glioma cells

AG D'Amico, S Scuderi, S Saccone, A Castorina… - Journal of Molecular …, 2013 - Springer
Emerging evidence have suggested that calorie restriction (CR) is a reliable method to
decrease cancer development since it produces changes in tumor microenvironment that …