End points and trial design in geriatric oncology research: a joint European organisation for research and treatment of cancer–Alliance for Clinical Trials in Oncology …
H Wildiers, M Mauer, A Pallis, A Hurria… - Journal of Clinical …, 2013 - ascopubs.org
Selecting the most appropriate end points for clinical trials is important to assess the value of
new treatment strategies. Well-established end points for clinical research exist in oncology …
new treatment strategies. Well-established end points for clinical research exist in oncology …
Patient income level and cancer clinical trial participation
JM Unger, DL Hershman, KS Albain… - Journal of Clinical …, 2013 - ascopubs.org
Purpose Studies have shown an association between socioeconomic status (SES) and
quality of oncology care, but less is known about the impact of patient SES on clinical trial …
quality of oncology care, but less is known about the impact of patient SES on clinical trial …
[HTML][HTML] Age is a prognostic factor affecting survival in lung cancer patients
F Tas, R Ciftci, L Kilic, S Karabulut - Oncology letters, 2013 - spandidos-publications.com
Despite all efforts at management, prognosis of advanced lung cancer is extremely poor,
with a median survival time of~ 1 year. The number of cancer patients aged> 70 years is …
with a median survival time of~ 1 year. The number of cancer patients aged> 70 years is …
[HTML][HTML] The challenges of enrolling older adults into intervention studies
NA Knechel - The Yale journal of biology and medicine, 2013 - ncbi.nlm.nih.gov
Adults aged 65 years or older have been routinely and systematically excluded from
research. With the number of older adults at a record high and growing faster than any other …
research. With the number of older adults at a record high and growing faster than any other …
The treatment of glioblastomas: a systematic update on clinical Phase III trials
Glioblastomas (GBMs) are invariably associated with unavoidable tumor recurrence and
overall poor prognosis. The present study is to summarize the results of clinical Phase III …
overall poor prognosis. The present study is to summarize the results of clinical Phase III …
[HTML][HTML] Elderly patients with advanced NSCLC in phase III clinical trials: are the elderly excluded from practice-changing trials in advanced NSCLC?
Introduction Elderly patients constitute the majority of patients with advanced non–small-cell
lung cancer (NSCLC). The median age of newly diagnosed patients with lung cancer in the …
lung cancer (NSCLC). The median age of newly diagnosed patients with lung cancer in the …
An increasing use of defunctioning stomas after low anterior resection for rectal cancer. Is this the way to go?
HS Snijders, CBM Van den Broek, M Wouters… - European Journal of …, 2013 - Elsevier
BACKGROUND: The last decade there has been an increased awareness of the problem of
anastomotic leakage after low anterior resection for rectal cancer, which may have led to …
anastomotic leakage after low anterior resection for rectal cancer, which may have led to …
Elderly patients with colon cancer have unique tumor characteristics and poor survival
BACKGROUND: The incidence of colon cancer increases with age, and colon cancer
predominantly affects individuals> 65 years old. However, there are limited data regarding …
predominantly affects individuals> 65 years old. However, there are limited data regarding …
Short‐term outcomes of craniotomy for malignant brain tumors in the elderly
A Seicean, S Seicean, NK Schiltz, N Alan, PK Jones… - Cancer, 2013 - Wiley Online Library
BACKGROUND. Disparity in resection rates for malignant brain tumors in elderly patients is
partially attributed to a belief that advanced age is associated with an increased risk of …
partially attributed to a belief that advanced age is associated with an increased risk of …
Effect of patient socioeconomic status on access to early-phase cancer trials
A Mohd Noor, D Sarker, S Vizor… - Journal of Clinical …, 2013 - ascopubs.org
Purpose Little is known about the influence of socioeconomic factors on patient access to
cancer trials. Differences should be considered to ensure generalizability of trial results and …
cancer trials. Differences should be considered to ensure generalizability of trial results and …