Macrophage heterogeneity in respiratory diseases
CE Boorsma, C Draijer, BN Melgert - Mediators of inflammation, 2013 - Wiley Online Library
Macrophages are among the most abundant cells in the respiratory tract, and they can have
strikingly different phenotypes within this environment. Our knowledge of the different …
strikingly different phenotypes within this environment. Our knowledge of the different …
The influence of cigarette smoking on viral infections: translating bench science to impact COPD pathogenesis and acute exacerbations of COPD clinically
CMT Bauer, MC Morissette, MR Stämpfli - Chest, 2013 - Elsevier
COPD is a complex syndrome that poses a serious health threat to> 1.1 billion smokers
worldwide. The stable disease is punctuated by episodes of acute exacerbation, which are …
worldwide. The stable disease is punctuated by episodes of acute exacerbation, which are …
Pulmonary hypertension in COPD: results from the ASPIRE registry
J Hurdman, R Condliffe, CA Elliot… - European …, 2013 - Eur Respiratory Soc
The phenotype and outcome of severe pulmonary hypertension in chronic obstructive
pulmonary disease (COPD) is described in small numbers, and predictors of survival are …
pulmonary disease (COPD) is described in small numbers, and predictors of survival are …
Imbalance between subpopulations of regulatory T cells in COPD
J Hou, Y Sun, Y Hao, J Zhuo, X Liu, P Bai, J Han… - Thorax, 2013 - thorax.bmj.com
Background Recent evidence indicates that human regulatory T cells (Tregs) are composed
of three distinct subpopulations: CD25++ CD45RA+ resting Tregs (rTregs), CD25+++ …
of three distinct subpopulations: CD25++ CD45RA+ resting Tregs (rTregs), CD25+++ …
Mechanisms of development of chronic obstructive pulmonary disease-associated pulmonary hypertension
JA Barberà - Pulmonary circulation, 2013 - journals.sagepub.com
Pulmonary hypertension is a prevalent complication of chronic obstructive pulmonary
disease (COPD) that is associated with poor prognosis. Although pulmonary hypertension is …
disease (COPD) that is associated with poor prognosis. Although pulmonary hypertension is …
Pathophysiology and clinical implications of pulmonary arterial enlargement in COPD
JM Wells, MT Dransfield - International journal of chronic …, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a complex condition defined by
progressive airflow limitation in response to noxious stimuli, inflammation, and vascular …
progressive airflow limitation in response to noxious stimuli, inflammation, and vascular …
Immunopathogenesis of chronic obstructive pulmonary disease
RA Holloway, LE Donnelly - Current opinion in pulmonary …, 2013 - journals.lww.com
Immunopathogenesis of chronic obstructive pulmonary disease : Current Opinion in
Pulmonary Medicine Immunopathogenesis of chronic obstructive pulmonary disease …
Pulmonary Medicine Immunopathogenesis of chronic obstructive pulmonary disease …
Increased expression of CD4+ IL-17+ cells in the lung tissue of patients with stable chronic obstructive pulmonary disease (COPD) and smokers
J Zhang, S Chu, X Zhong, Q Lao, Z He… - International …, 2013 - Elsevier
CD4+ IL-17+ cells have an important role in controlling immune and inflammatory reactions.
The authors of the present study hypothesize that these cells may be involved in the …
The authors of the present study hypothesize that these cells may be involved in the …
Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease
BL Eppert, BW Wortham, JL Flury… - The Journal of …, 2013 - journals.aai.org
Cigarette smoke (CS) exposure is the primary risk factor for the development of chronic
obstructive pulmonary disease (COPD). COPD is characterized by chronic peribronchial …
obstructive pulmonary disease (COPD). COPD is characterized by chronic peribronchial …
[HTML][HTML] Lung CD8+ T cells in COPD have increased expression of bacterial TLRs
CM Freeman, FJ Martinez, MLK Han, GR Washko… - Respiratory …, 2013 - Springer
Abstract Background Toll-like receptors (TLRs) on T cells can modulate their responses,
however, the extent and significance of TLR expression by lung T cells, NK cells, or NKT …
however, the extent and significance of TLR expression by lung T cells, NK cells, or NKT …