Two-component systems in Streptomyces: key regulators of antibiotic complex pathways
Streptomyces, the main antibiotic-producing bacteria, responds to changing environmental
conditions through a complex sensing mechanism and two-component systems (TCSs) play …
conditions through a complex sensing mechanism and two-component systems (TCSs) play …
Bacillus subtilis: from soil bacterium to super-secreting cell factory
JM van Dijl, M Hecker - Microbial cell factories, 2013 - Springer
The biotechnology industry has become a key element in modern societies. Within this
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
Engineering microbial cells for the biosynthesis of natural compounds of pharmaceutical significance
P Jeandet, Y Vasserot, T Chastang… - BioMed research …, 2013 - Wiley Online Library
Microbes constitute important platforms for the biosynthesis of numerous molecules of
pharmaceutical interest such as antitumor, anticancer, antiviral, antihypertensive …
pharmaceutical interest such as antitumor, anticancer, antiviral, antihypertensive …
Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus
Mithramycin (MTM) is a polyketide antitumor compound produced by Streptomyces
argillaceus constituted by a tricyclic aglycone with two aliphatic side chains, a trisaccharide …
argillaceus constituted by a tricyclic aglycone with two aliphatic side chains, a trisaccharide …
Metabolic engineering of Lactobacillus plantarum for succinic acid production through activation of the reductive branch of the tricarboxylic acid cycle
A Tsuji, S Okada, P Hols, E Satoh - Enzyme and microbial technology, 2013 - Elsevier
Biosynthesis of succinic acid is an alternative method from conventional chemical synthesis.
For this application, several bacteria and fungi have been employed and genetically …
For this application, several bacteria and fungi have been employed and genetically …
Physiological and Molecular Timing of the Glucose to Acetate Transition in Escherichia coli
The glucose-acetate transition in Escherichia coli is a classical model of metabolic
adaptation. Here, we describe the dynamics of the molecular processes involved in this …
adaptation. Here, we describe the dynamics of the molecular processes involved in this …
The main byproducts and metabolic flux profiling of γ-PGA-producing strain B. subtilis ZJU-7 under different pH values
F Zhu, J Cai, X Wu, J Huang, L Huang, J Zhu… - Journal of …, 2013 - Elsevier
Poly-γ-glutamic acid (γ-PGA) is an extracellular anionic polymer with many potential
applications. Although microbial fermentation is the common approach to produce γ-PGA …
applications. Although microbial fermentation is the common approach to produce γ-PGA …
Recent progress in metabolic engineering for the production of biofuels and biochemicals from renewable sources with particular emphasis on catabolite regulation …
R Yao, K Shimizu - Process Biochemistry, 2013 - Elsevier
Recent metabolic engineering practice was briefly reviewed including the case where a
mixture of multiple sugars obtained from lignocellulose, etc. was used as a carbon source to …
mixture of multiple sugars obtained from lignocellulose, etc. was used as a carbon source to …
基因工程菌发酵生产L-乳酸研究进展
姜旭， 王丽敏， 张桂敏， 于波， 曾庆韬 - 生物工程学报, 2013 - cqvip.com
乳酸是重要的工业平台化学品. 随着聚乳酸产业的兴起, 对高质量L-乳酸的需求量也不断增加.
为了进一步降低L-乳酸发酵成本, 提高菌株的工业适应性, 各种现代生物技术已经应用到L …
为了进一步降低L-乳酸发酵成本, 提高菌株的工业适应性, 各种现代生物技术已经应用到L …
Revealing natural antisense transcripts from Plasmodium vivax isolates: evidence of genome regulation in complicated malaria
PA Boopathi, AK Subudhi, S Garg, S Middha… - Infection, Genetics and …, 2013 - Elsevier
Plasmodium vivax is the most geographically widespread human malaria parasite causing
approximately 130–435 million infections annually. It is an economic burden in many parts …
approximately 130–435 million infections annually. It is an economic burden in many parts …