[PDF][PDF] The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow

P Blinder, PS Tsai, JP Kaufhold, PM Knutsen… - Nature …, 2013 - nature.com
What is the nature of the vascular architecture in the cortex that allows the brain to meet the
energy demands of neuronal computations? We used high-throughput histology to …

Glucose metabolism in normal aging and Alzheimer's disease: methodological and physiological considerations for PET studies

L Mosconi - Clinical and translational imaging, 2013 - Springer
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

Hypertension, brain damage and cognitive decline

D Gąsecki, M Kwarciany, W Nyka… - Current hypertension …, 2013 - Springer
Loss of cognitive function is one the most devastating manifestations of ageing and vascular
disease. Cognitive decline is rapidly becoming an important cause of disability worldwide …

The virtual brain integrates computational modeling and multimodal neuroimaging

P Ritter, M Schirner, AR McIntosh, VK Jirsa - Brain connectivity, 2013 - liebertpub.com
Brain function is thought to emerge from the interactions among neuronal populations. Apart
from traditional efforts to reproduce brain dynamics from the micro-to macroscopic scales …

A review of calibrated blood oxygenation level‐dependent (BOLD) methods for the measurement of task‐induced changes in brain oxygen metabolism

NP Blockley, VEM Griffeth, AB Simon… - NMR in …, 2013 - Wiley Online Library
The dynamics of the blood oxygenation level‐dependent (BOLD) response are dependent
on changes in cerebral blood flow, cerebral blood volume and the cerebral metabolic rate of …

Locus coeruleus stimulation recruits a broad cortical neuronal network and increases cortical perfusion

X Toussay, K Basu, B Lacoste… - Journal of Neuroscience, 2013 - Soc Neuroscience
The locus coeruleus (LC), the main source of brain noradrenalin (NA), modulates cortical
activity, cerebral blood flow (CBF), glucose metabolism, and blood–brain barrier …

Resolving the transition from negative to positive blood oxygen level-dependent responses in the developing brain

MG Kozberg, BR Chen, SE DeLeo… - Proceedings of the …, 2013 - National Acad Sciences
The adult brain exhibits a local increase in cortical blood flow in response to external
stimulus. However, broadly varying hemodynamic responses in the brains of newborn and …

Fast hemodynamic responses in the visual cortex of the awake mouse

MA Pisauro, NT Dhruv, M Carandini… - Journal of …, 2013 - Soc Neuroscience
Hemodynamic responses in mice and other species are typically measured under
anesthesia. However, anesthesia could influence their relationship to neural activity. To …