The implication of vitamin D and autoimmunity: a comprehensive review

CY Yang, PSC Leung, IE Adamopoulos… - Clinical reviews in …, 2013 - Springer
Historically, vitamin D has been associated with the regulation of bone metabolism.
However, increasing evidence demonstrates a strong association between vitamin D …

The role of vitamin d deficiency in the incidence, progression, and complications of type 1 diabetes mellitus

M Chakhtoura, ST Azar - International journal of endocrinology, 2013 - Wiley Online Library
The “nonclassic” role of 1, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) has been recently
widely recognized. In type 1 diabetes mellitus (T1D), it plays an immunomodulatory role …

Role of vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D level in Egyptian female patients with systemic lupus erythematosus

AA Emerah, AS El-Shal - Molecular biology reports, 2013 - Springer
Recently, several studies have demonstrated the role of vitamin D receptor (VDR)
polymorphisms in the development of systemic lupus erythematosus (SLE). We aimed to …

Investigation of the vitamin D receptor gene (VDR) and its interaction with protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) on risk of islet …

B Frederiksen, E Liu, J Romanos, AK Steck… - The Journal of Steroid …, 2013 - Elsevier
The present study investigated the association between variants in the vitamin D receptor
gene (VDR) and protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2), as well …

Relationship between vitamin D receptor gene polymorphisms and migraine without aura in an Iranian population

M Motaghi, S Haghjooy Javanmard… - BioMed research …, 2013 - Wiley Online Library
Background. Inflammation has a key role in migraine pathophysiology. Vitamin D is an
effective anti‐inflammatory agent. The aim of this study was to investigate the association …

[PDF][PDF] Vitamin D receptor (VDR) gene polymorphisms and susceptibility to systemic lupus erythematosus clinical manifestations

J de Azevêdo Silva, K Monteiro Fernandes… - Lupus, 2013 - researchgate.net
Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical
manifestations and target tissue damage. Currently, several genes have been associated …

The Cdx-2 polymorphism in the VDR gene is associated with increased risk of cancer: a meta-analysis

J Huang, J Huang, Y Ma, H Wang, J Yang… - Molecular biology …, 2013 - Springer
The Cdx-2 polymorphism in VDR gene has been extensively investigated for association
with cancer risk, however, results of different studies have been inconsistent. The objective …

Vitamin D receptor (VDR) gene polymorphisms and susceptibility to systemic lupus erythematosus clinical manifestations

JA Silva, KM Fernandes, JAT Pancotto, TS Fragoso… - Lupus, 2013 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical
manifestations and target tissue damage. Currently, several genes have been associated …

[PDF][PDF] Molecular analysis of vitamin D receptor gene polymorphisms rs2228570 (FokI) and rs1544410 (BsmI) in patients with Behcet's Disease

H Khodadadi, A Khabazi, SMH Ghaderian… - Life Science …, 2013 - academia.edu
Recent studies have shown vitamin D3 has immune-modulatory effect. The functional
differences in the immune-modulatory action of vitamin D is mediated via the vitamin D …

[PDF][PDF] Association of vitamin D receptors genes polymorphism (Apa I, and Taq I) with type 1 diabetes in Saudi Arabia (KSA)

ES El-Badrawy, ZS Ibrahim, AA Aziz, MM Kamel… - Life Sci J, 2013 - academia.edu
Type 1 diabetes mellitus (TIDM) results from an immune-mediated destruction of insulin-
producing-cells in the pancreatic islets of Langerhans. There are clear differences in …