Neural plasticity in the gastrointestinal tract: chronic inflammation, neurotrophic signals, and hypersensitivity

IE Demir, KH Schäfer, E Tieftrunk, H Friess… - Acta …, 2013 - Springer
Neural plasticity is not only the adaptive response of the central nervous system to learning,
structural damage or sensory deprivation, but also an increasingly recognized common …

Acid sensitization of esophageal mucosal afferents: implication for symptom perception in patients across the gastroesophageal reflux disease spectrum

MM Szczesniak, SE Fuentealba… - The Clinical journal of …, 2013 - journals.lww.com
Background: Sensitization of esophageal chemoreceptors, either directly by intermittent acid
exposure or indirectly through esophagitis-associated inflammatory mediators, is likely to be …

High expression of calcitonin gene-related peptide and substance P in esophageal mucosa of patients with non-erosive reflux disease

X Xu, Z Li, D Zou, M Yang, Z Liu, X Wang - Digestive diseases and …, 2013 - Springer
Background Visceral hypersensitivity is an important etiology of non-erosive reflux disease
(NERD). Calcitonin gene-related peptide (CGRP) and substance P (SP) are involved in the …

Emerging therapeutic options in GERD

P Woodland, G Amarasinghe, D Sifrim - Best Practice & Research Clinical …, 2013 - Elsevier
Gastroesophageal reflux disease (GERD) is a prevalent problem resulting in a high level of
healthcare consultation and expenditure in the Western World. Although standard medical …

老年GERD 患者的临床特征及诊治进展

张小兰, 潘庆敏, 严洁, 张小乔, 陈芳, 屈红 - Medical Diagnosis, 2013 - hanspub.org
目的: 分析老年胃食管反流病(gast roesophageal reflux disease, GERD) 患者临床症状特征,
并观察疗效. 方法: 随机选取2011-01/2012-01 我院消化内科, 老年科门诊及住院部病房符合 …

The Role of Acid Reflux in Non‐Cardiac Chest Pain

C Almansa, SR Achem - Practical Manual of Gastroesophageal …, 2013 - Wiley Online Library
Non‐cardiac chest pain is a common and debilitating condition. Gastroesophageal reflux is
the most common esophageal cause of non‐cardiac chest pain. Despite the fact that a …

Oesophageal mucosal integrity in non-erosive reflux disease and refractory GORD.

PJ Woodland - 2013 - qmro.qmul.ac.uk
Background: 20 to 30% of patients with GORD respond inadequately to conventional
therapy. Most of these patients belong to the non-‐erosive reflux disease group. Despite not …

[PDF][PDF] Clinical Manifestations of GERD Aged Patients and Progress of Treatment

X Zhang, Q Pan, J Yan, X Zhang, F Chen, H Qu - 2013 - pdf.hanspub.org
Aim: To analyze the clinical symptoms of aged patients with gastroesophageal reflux
disease (GERD) and to observe the curative effect of comprehensive treatment for GERD …

[引用][C] 升降并举法治疗非糜烂性胃食管反流病的临床研究

秦嫣, 范怀玲, 朱凌云, 朱远镕, 宋宏伟, 杨芸峰 - 世界中医药, 2013