Mitochondria constitute an important topic of biomedical enquiry (one paper in every 154
indexed in PubMed since 1998 is retrieved by the keyword 'mitochondria') because of …

There has been substantial recent interest in the possible role of oxidative stress as a
mechanism underlying life-history trade-offs, particularly with regard to reproductive costs …

Aging can be viewed as a quasi-programmed phenomenon driven by the overactivation of
the nutrient-sensing mTOR gerogene. mTOR-driven aging can be triggered or accelerated …

A central principle in life-history theory is that reproductive effort negatively affects survival.
Costs of reproduction are thought to be physiologically based, but the underlying …

Oxidative stress–the imbalance between reactive oxygen species (ROS) and neutralising
antioxidants–has been under debate as the main cause of ageing in aerobial organisms …

The elucidation of the intriguing relationship between oxidative stress and Alzheimer's
disease is crucial to understand the pathogenesis of the disease as also to design a suitable …

Aging is an extremely complex and multifactorial process that proceeds to the gradual dete‐-
rioration in functions. It usually manifest after maturity and leads to disability and death …

While oxidative damage owing to reactive oxygen species (ROS) often increases with
advancing age and is associated with many age-related diseases, its causative role in …

High peak metabolic rates may provide a performance advantage, but it may also entail a
physiological cost. A long-held assumption is that high mass-specific energy expenditure is …

Glutathione (GSH) and GSH-dependent enzymes play a key role in cellular detoxification
processes that enable organism to cope with various internal and environmental stressors …