Background: Vitamin and mineral supplements are commonly used to prevent chronic
diseases. Purpose: To systematically review evidence for the benefit and harms of vitamin …

Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

There are multiple sources of reactive oxygen species (ROS) in the cell. As a major site of
ROS production, mitochondria have drawn considerable interest because it was recently …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Objective To assess the efficacy of vitamin and antioxidant supplements in the prevention of
cardiovascular diseases. Design Meta-analysis of randomised controlled trials. Data …

Significance: Vitamin C, or ascorbic acid, has long been known to participate in several
important functions in the vascular bed in support of endothelial cells. These functions …

The oxidative modification hypothesis of atherosclerosis, which assigns to oxidized low‐
density lipoproteins (LDLs) a crucial role in atherosclerosis initiation and progression, is still …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Background and Aims Evidence shows that antioxidant supplements may increase mortality.
Our aims were to assess whether different doses of beta-carotene, vitamin A, and vitamin E …

Spatiotemporal regulation of the activity of a vast array of intracellular proteins and signaling
pathways by reactive oxygen species (ROS) governs normal cardiovascular function …