Polyethylenimines for siRNA and miRNA delivery in vivo
S Höbel, A Aigner - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
The discovery of RNA interference (RNAi) as a naturally occurring mechanism for gene
knockdown has attracted considerable attention toward the use of small interfering RNAs …
knockdown has attracted considerable attention toward the use of small interfering RNAs …
Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly (amidoamine) for siRNA delivery
CJ Chen, JC Wang, EY Zhao, LY Gao, Q Feng, XY Liu… - Biomaterials, 2013 - Elsevier
In this study, a series of bioreducible poly (amidoamine) s grafting different percentages of
cholesterol (rPAA-Ch14: 14%, rPAA-Ch29: 29%, rPAA-Ch57: 57% and rPAA-Ch87: 87%) …
cholesterol (rPAA-Ch14: 14%, rPAA-Ch29: 29%, rPAA-Ch57: 57% and rPAA-Ch87: 87%) …
A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation
Polycations have been explored as non-viral carriers for effective delivery of small interfering
RNA (siRNA). Modifying polycations such as polyethylenimine (PEI) with lipid substitution …
RNA (siRNA). Modifying polycations such as polyethylenimine (PEI) with lipid substitution …
Vehicles for Small Interfering RNA transfection: Exosomes versus Synthetic Nanocarriers
M Duechler - DNA and RNA Nanotechnology, 2013 - degruyter.com
Therapies based on RNA interference (RNAi) hold a great potential for targeted interference
of the expression of specific genes. Small-interfering RNAs (siRNA) and micro-RNAs …
of the expression of specific genes. Small-interfering RNAs (siRNA) and micro-RNAs …
Effective Tumor Treatment by VEGF si RNA Complexed with Hydrophobic Poly (A mino Acid)‐M odified Polyethylenimine
Two copolymers are designed and synthesised for siRNA delivery based on
polyethylenimine by grafting hydrophilic acrylamide segments and hydrophobic poly (γ …
polyethylenimine by grafting hydrophilic acrylamide segments and hydrophobic poly (γ …
水溶性脂质体运载基因药物复合物治疗大鼠神经病理性痛
胡春奎， 陆建华， 陈昊， 熊家祥 - 中国组织工程研究, 2013 - cjter.com
背景: 有研究报道病毒载体运载N-甲基-D 天冬氨酸受体1 小干扰RNA 可有效缓解大鼠炎性疼痛,
但病毒载体存在安全隐患. 目的: 探讨水溶性脂质体运载N-甲基-D 天冬氨酸受体1 小干扰RNA …
但病毒载体存在安全隐患. 目的: 探讨水溶性脂质体运载N-甲基-D 天冬氨酸受体1 小干扰RNA …
Water-soluble lipopolymer carrying gene drugs for treatment of neuropathic pain in rats
C Hu, J Lu, H Chen, J Xiong - Chinese Journal of Tissue Engineering …, 2013 - cjter.com
BACKGROUND: Some studies have shown that viral vectors can carry N-methyl-D-aspartic
acid receptors 1 (NR1) small interference RNA (siRNA) to relieve inflammatory pain in rats …
acid receptors 1 (NR1) small interference RNA (siRNA) to relieve inflammatory pain in rats …
[图书][B] Novel Phospholipid-modified-polyethylenimine (PLPEI)-based-Nanocarriers for siRNA Delivery
S Essex - 2013 - search.proquest.com
This project was designed with a clear aim of developing effective, novel, non-viral siRNA
nanocarriers for further application in the treatment of Cancer. Micelle-like nanoparticles …
nanocarriers for further application in the treatment of Cancer. Micelle-like nanoparticles …