Myocardial infarct size is a major determinant of prognosis. Ischaemic preconditioning with
brief coronary occlusion and reperfusion before a sustained period of coronary occlusion …

Coronary heart disease (CHD) is the leading cause of death and disability worldwide.
Despite current therapy, the morbidity and mortality for patients with CHD remains …

Background Remote ischaemic preconditioning has been associated with reduced risk of
myocardial injury after coronary artery bypass graft (CABG) surgery. We investigated the …

Both preclinical and clinical studies suggest that brief cycles of ischemia and reperfusion in
the arm or leg may protect the heart against injury following prolonged coronary artery …

Organ or tissue dysfunction due to acute ischemia–reperfusion injury (IRI) is the leading
cause of death and disability worldwide. Acute IRI induces cell injury and death in a wide …

Myocardial conditioning is an endogenous cardioprotective phenomenon that profoundly
limits infarct size in experimental models. The current challenge is to translate this paradigm …

Background Remote ischemic preconditioning (RIPC) has been shown to enhance the
tolerance of remote organs to cope with a subsequent ischemic event. We hypothesized that …

OBJECTIVE: Clinical trials on cardioprotection by remote ischemic preconditioning (RIPC)
for adult patients undergoing cardiac surgery revealed mixed results. Previous meta …

Stroke is a major cause of morbidity and mortality, and activation of the immune system can
impact on stroke outcome. Although the majority of research has focused on the role of the …

Acute kidney injury (AKI) after any type of intervention negatively impacts mortality, length of
hospitalization, and perhaps long-term survival. In the case of endovascular aneurysm …