[HTML][HTML] lincRNAs: genomics, evolution, and mechanisms

I Ulitsky, DP Bartel - Cell, 2013 - cell.com
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in
mammalian genomes and might play widespread roles in gene regulation and other cellular …

On the classification of long non-coding RNAs

L Ma, VB Bajic, Z Zhang - RNA biology, 2013 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide
variety of important biological processes. To make easier interpretation of lncRNA …

Structure and function of long noncoding RNAs in epigenetic regulation

TR Mercer, JS Mattick - Nature structural & molecular biology, 2013 - nature.com
Genomes of complex organisms encode an abundance and diversity of long noncoding
RNAs (lncRNAs) that are expressed throughout the cell and fulfill a wide variety of regulatory …

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs

MJ Hangauer, IW Vaughn, MT McManus - PLoS genetics, 2013 - journals.plos.org
Known protein coding gene exons compose less than 3% of the human genome. The
remaining 97% is largely uncharted territory, with only a small fraction characterized. The …

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

F Lai, UA Orom, M Cesaroni, M Beringer, DJ Taatjes… - Nature, 2013 - nature.com
Recent advances in genomic research have revealed the existence of a large number of
transcripts devoid of protein-coding potential in multiple organisms,,,,,,,. Although the …

Long noncoding RNAs: past, present, and future

JTY Kung, D Colognori, JT Lee - Genetics, 2013 - academic.oup.com
Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …

Function of lncRNAs and approaches to lncRNA-protein interactions

JJ Zhu, HJ Fu, YG Wu, XF Zheng - Science China Life Sciences, 2013 - Springer
Long non-coding RNAs (lncRNAs), which represent a new frontier in molecular biology, play
important roles in regulating gene expression at epigenetic, transcriptional and post …

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

P Wu, X Zuo, H Deng, X Liu, L Liu, A Ji - Brain research bulletin, 2013 - Elsevier
Long noncoding RNAs (lncRNAs) have been attracting immense research interest, while
only a handful of lncRNAs have been characterized thoroughly. Their involvement in the …

Ribosome profiling reveals resemblance between long non-coding RNAs and 5′ leaders of coding RNAs

GL Chew, A Pauli, JL Rinn, A Regev… - …, 2013 - journals.biologists.com
Large-scale genomics and computational approaches have identified thousands of putative
long non-coding RNAs (lncRNAs). It has been controversial, however, as to what fraction of …

Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol

A Bhan, I Hussain, KI Ansari, S Kasiri, A Bashyal… - Journal of molecular …, 2013 - Elsevier
Abstract HOTAIR (HOX antisense intergenic RNA) is a long noncoding RNA (lncRNA) that is
transcribed from the antisense strand of homeobox C gene locus in chromosome 12 …