Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review

A Tsamis, JT Krawiec, DA Vorp - Journal of the royal …, 2013 - royalsocietypublishing.org
Aortic disease is a significant cause of death in developed countries. The most common
forms of aortic disease are aneurysm, dissection, atherosclerotic occlusion and ageing …

Toward patient-specific simulations of cardiac valves: state-of-the-art and future directions

E Votta, TB Le, M Stevanella, L Fusini, EG Caiani… - Journal of …, 2013 - Elsevier
Recent computational methods enabling patient-specific simulations of native and prosthetic
heart valves are reviewed. Emphasis is placed on two critical components of such …

Measurements of mechanical anisotropy in brain tissue and implications for transversely isotropic material models of white matter

Y Feng, RJ Okamoto, R Namani, GM Genin… - Journal of the mechanical …, 2013 - Elsevier
White matter in the brain is structurally anisotropic, consisting largely of bundles of aligned,
myelin-sheathed axonal fibers. White matter is believed to be mechanically anisotropic as …

Multiaxial mechanical properties and constitutive modeling of human adipose tissue: a basis for preoperative simulations in plastic and reconstructive surgery

G Sommer, M Eder, L Kovacs, H Pathak, L Bonitz… - Acta biomaterialia, 2013 - Elsevier
A preoperative simulation of soft tissue deformations during plastic and reconstructive
surgery is desirable to support the surgeon's planning and to improve surgical outcomes …

Multi-scale mechanics of traumatic brain injury: predicting axonal strains from head loads

RJH Cloots, JAW Van Dommelen, S Kleiven… - … and modeling in …, 2013 - Springer
The length scales involved in the development of diffuse axonal injury typically range from
the head level (ie, mechanical loading) to the cellular level. The parts of the brain that are …

Finite element modeling of mitral valve dynamic deformation using patient-specific multi-slices computed tomography scans

Q Wang, W Sun - Annals of biomedical engineering, 2013 - Springer
The objective of this study was to develop a patient-specific finite element (FE) model of a
human mitral valve. The geometry of the mitral valve was reconstructed from multi-slice …

An automated approach for three-dimensional quantification of fibrillar structures in optically cleared soft biological tissues

AJ Schriefl, H Wolinski, P Regitnig… - Journal of the …, 2013 - royalsocietypublishing.org
We present a novel approach allowing for a simple, fast and automated morphological
analysis of three-dimensional image stacks (z-stacks) featuring fibrillar structures from …

A multiscale computational approach to estimating axonal damage under inertial loading of the head

RM Wright, A Post, B Hoshizaki… - Journal of …, 2013 - liebertpub.com
A computational modeling framework is developed to estimate the location and degree of
diffuse axonal injury (DAI) under inertial loading of the head. DAI is one of the most common …

The role of geometric and biomechanical factors in abdominal aortic aneurysm rupture risk assessment

SS Raut, S Chandra, J Shum, EA Finol - Annals of biomedical engineering, 2013 - Springer
The current clinical management of abdominal aortic aneurysm (AAA) disease is based to a
great extent on measuring the aneurysm maximum diameter to decide when timely …

A hyperelastic biphasic fibre-reinforced model of articular cartilage considering distributed collagen fibre orientations: continuum basis, computational aspects and …

DM Pierce, T Ricken, GA Holzapfel - Computer methods in …, 2013 - Taylor & Francis
Cartilage is a multi-phase material composed of fluid and electrolytes (68–85% by wet
weight), proteoglycans (5–10% by wet weight), chondrocytes, collagen fibres and other …