Opiates are among the oldest medications available to manage a number of medical
problems. Although pain is the current focus, early use initially focused upon the treatment of …

Inflammation is the process by which an organism responds to tissue injury involving both
immune cell recruitment and mediator release. Diverse causes of neuropathic pain are …

Chronic pain conditions are associated with abnormalities in brain structure and function.
Moreover, some studies indicate that brain activity related to the subjective perception of …

The objective of the present study was to evaluate the antinociceptive effects of phytol using
chemical and thermal models of nociception in mice and to assess its antioxidant effects in …

Common cancers, including cancers of the breast, lung, and prostate, frequently metastasize
to multiple bones where they can cause significant and life-altering pain. Similar to cancer …

There are two basic categories of pain: physiological pain, which serves an important
protective function, and pathological pain, which can have a major negative impact on …

Physical pain can be clearly distinguished from other states of distress. In recent years,
however, the notion that social distress is experienced as physically painful has permeated …

The term 'neurogenic inflammation'has been adopted to describe the local release of
inflammatory mediators, such as substance P and calcitonin gene‐related peptide, from …

525,891 A 9/1894 Fricke 3,724,467 A 4/1973 Avery et a1. 3,845,770 A 11/1974 Theeuwes et
a1. 3,916,899 A 11/1975 Theeuwes et a1. 4,141,367 A 2/1979 Ferreira 4,232,679 A 11/1980 …

Environmentally caused changes in chromosomes that do not alter the DNA sequence but
cause phenotypic changes by altering gene transcription are summarized as epigenetics. A …