Medical therapies for hepatocellular carcinoma: a critical view of the evidence

A Villanueva, V Hernandez-Gea… - … reviews Gastroenterology & …, 2013 - nature.com
The management of hepatocellular carcinoma (HCC) has substantially changed in the past
few decades. Improvements in patient stratification (for example, using the Barcelona Clinic …

[HTML][HTML] Liver immunology

DP Bogdanos, B Gao, ME Gershwin - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …

Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention

WH Wen, MH Chang, LL Zhao, YH Ni, HY Hsu… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Immunoprophylaxis reduces but does not completely eradicate
hepatitis B virus (HBV) transmission. This prospective study aims at assessing the rate and …

The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention

YC Lee, THH Chen, HM Chiu, CT Shun, H Chiang… - Gut, 2013 - gut.bmj.com
Objective To evaluate the benefit of mass eradication of Helicobacter pylori infection in
reducing premalignant gastric lesions. Design Mass eradication of H pylori infection was …

[PDF][PDF] Prevention of hepatitis B virus–related hepatocellular carcinoma with antiviral therapy

CL Lai, MF Yuen - Hepatology, 2013 - Wiley Online Library
Chronic hepatitis B (CHB) infection is the major cause of hepatocellular carcinoma (HCC).
Primary prevention of hepatitis B infection by vaccination is effective in reducing the …

Plant-derived virus-like particles as vaccines

Q Chen, H Lai - Human vaccines & immunotherapeutics, 2013 - Taylor & Francis
Virus-like particles (VLPs) are self-assembled structures derived from viral antigens that
mimic the native architecture of viruses but lack the viral genome. VLPs have emerged as a …

Current progress in development of hepatitis C virus vaccines

TJ Liang - Nature medicine, 2013 - nature.com
Despite major advances in the understanding and treatment of hepatitis C, a preventive
vaccine remains elusive. The marked genetic diversity and multiple mechanisms of …

Observational study of vaccine efficacy 24 years after the start of hepatitis B vaccination in two Gambian villages: no need for a booster dose

M Mendy, I Peterson, S Hossin, T Peto, ML Jobarteh… - PloS one, 2013 - journals.plos.org
Objectives To determine the duration of protection from hepatitis B vaccine given in infancy
and early childhood and asses risk factors for HBV infection and chronic infection. Methods …

Hepatocellular carcinoma: epidemiology, biology, diagnosis, and therapies

MA Gomes, DG Priolli, JG Tralhao… - Revista da Associação …, 2013 - Elsevier
Hepatocellular carcinoma is the fifth most common cancer in men and the seventh in
women, as is diagnosed in more than half a million individuals worldwide every year. In …

[HTML][HTML] Diagnosis of and therapy for hepatocellular carcinoma

TF Greten, NP Malek, S Schmidt, J Arends… - Zeitschrift fur …, 2013 - ncbi.nlm.nih.gov
The interdisciplinary guidelines at the S3 level on the diagnosis of and therapy for
hepatocellular carcinoma (HCC) constitute an evidence-and consensus-based instrument …