[PDF][PDF] Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway
Damaged DNA is an obstacle during DNA replication and a cause of genome instability and
cancer. To bypass this problem, eukaryotes activate DNA damage tolerance (DDT) …
cancer. To bypass this problem, eukaryotes activate DNA damage tolerance (DDT) …
Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit
R Kelly, SK Davey - PloS one, 2013 - journals.plos.org
Genomic integrity is preserved by checkpoints, which act to delay cell cycle progression in
the presence of DNA damage or replication stress. The heterotrimeric Rad9-Rad1-Hus1 (9-1 …
the presence of DNA damage or replication stress. The heterotrimeric Rad9-Rad1-Hus1 (9-1 …
[HTML][HTML] Origin, recognition, signaling and repair of DNA double-strand breaks in mammalian cells
LH Thompson, CL Limoli - Madame Curie Bioscience Database …, 2013 - ncbi.nlm.nih.gov
Achromosomal double-strand break (DSB) can arise from multiple sources including
ionizing radiation and DNA replication itself. An understanding of the intricate pro tein …
ionizing radiation and DNA replication itself. An understanding of the intricate pro tein …
NBS 1 directly activates ATR independently of MRE 11 and TOPBP 1
M Kobayashi, N Hayashi, M Takata… - Genes to Cells, 2013 - Wiley Online Library
NBS 1 plays unique and essential roles in ATM activation in response to DNA double‐strand
breaks. We found that CHK 1 phosphorylation and FANCD 2 ubiquitination induced by …
breaks. We found that CHK 1 phosphorylation and FANCD 2 ubiquitination induced by …
Role of the checkpoint clamp in DNA damage response
M Kai - Biomolecules, 2013 - mdpi.com
DNA damage occurs during DNA replication, spontaneous chemical reactions, and assaults
by external or metabolism-derived agents. Therefore, all living cells must constantly contend …
by external or metabolism-derived agents. Therefore, all living cells must constantly contend …
The rad1 gene in Rainbow Trout (Oncorhynchus mykiss) is highly conserved and may express proteins from non-canonical spliced isoforms
J Bozdarov, JP Sherry, BP Duncker, NC Bols… - … and Physiology Part C …, 2013 - Elsevier
Cell-cycle checkpoint proteins maintain genomic integrity by sensing damaged DNA and
initiating DNA repair or apoptosis. RAD1 is a checkpoint protein involved in the sensing of …
initiating DNA repair or apoptosis. RAD1 is a checkpoint protein involved in the sensing of …
[图书][B] Roles for the DNA damage checkpoint gene Hus1 in responding to endogenous and exogenous stresses in vivo
G Balmus - 2013 - search.proquest.com
The DNA damage response (DDR) represents the primary line of defense against
exogenous and endogenous genotoxic agents that threaten the stability of our genomes …
exogenous and endogenous genotoxic agents that threaten the stability of our genomes …
[图书][B] Modifications of DNA clamps and their role in DNA damage management
N Wit - 2013 - dare.uva.nl
The generation of high affinity antibodies in B cells critically depends on translesion
synthesis (TLS) polymerases that introduce mutations into immunoglobulin genes during …
synthesis (TLS) polymerases that introduce mutations into immunoglobulin genes during …
[图书][B] Mechanism of DNA Homologous Recombination through Studies of DNA Sliding Clamps, Clamp Loaders, and DNA Polymerases
J Li - 2013 - search.proquest.com
DNA double-strand breaks (DSBs) are introduced into the genome by several factors
including ionizing radiation, mutagenic chemicals, reactive oxygen species, and stalled DNA …
including ionizing radiation, mutagenic chemicals, reactive oxygen species, and stalled DNA …
[引用][C] SOURCE (OR PART OF THE FOLLOWING SOURCE): Type PhD thesis Title Modifications of DNA clamps and their role in DNA damage management
N Wit - 2013