Presynaptic inhibition of gamma lobe neurons is required for olfactory learning in Drosophila

S Zhang, G Roman - Current Biology, 2013 - cell.com
The loss of heterotrimeric G (o) signaling through the expression of pertussis toxin (PTX)
within either the α/β or γ lobe mushroom body neurons of Drosophila results in the impaired …

A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels

R Mahajan, J Ha, M Zhang, T Kawano, T Kozasa… - Science …, 2013 - science.org
The atrial G protein (heterotrimeric guanine nucleotide–binding protein)–regulated inwardly
rectifying K+ (GIRK1 and GIRK4) heterotetrameric channels underlie the acetylcholine …

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

X Wang, B Liang, L Skibsbye, SP Olesen… - Journal of …, 2013 - journals.lww.com
G protein–coupled inwardly rectifying K+ channels (GIRK) are important in the regulation of
heart rate and atrial electrophysiology. GIRK channels are activated by G protein–coupled …

Genetic Variations in the KCNJ5 Gene in Primary Aldosteronism Patients from Xinjiang, China

NF Li, HJ Li, DL Zhang, JH Zhang, XG Yao, HM Wang… - PLoS …, 2013 - journals.plos.org
Background Primary aldosteronism (PA) is the most common endocrine form of secondary
hypertension, and one of the most common subtypes of sporadic PA is aldosterone …

Heterogeneity of Inward Rectifier

M YAMADA, C KONDO… - Molecular and Cellular …, 2013 - books.google.com
Three background inward rectifier potassium channels were isolated from a mouse brain
cDNA library. Based on their amino acid sequences and the electrophysiological properties …

[图书][B] Optogenetic Tool Development and Interrogation of Frequency-Dependent Signaling in the Hippocamposeptal Pathway

JH Mattis - 2013 - search.proquest.com
Hippocampal oscillations are critical for information processing, and are strongly influenced
by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory …

A Computational Model Reveals the Action of Gβγ at an Inter-Subunit Cleft to Activate GIRK1 Channels

R Mahajan, J Ha, M Zhang, T Kawano, T Kozasa… - 2013 - digitalcommons.chapman.edu
The atrial G protein-regulated inwardly rectifying K+(GIRK1 and GIRK4) heterotetrameric
channels underlie the acetylcholine-induced K+ current responsible for vagal inhibition of …

[PDF][PDF] 新たに同定されたカリウムチャネルの立体構造解析と留学記

日下部吉男 - showa.repo.nii.ac.jp
要 旨 K+ チャネル分子は, カリウムイオン (K+) だけを高速かつ選択的に通す分子で,
細胞一般の静止膜電位の制御や, 興奮性細胞の発火パターンの決定に重要な役割を果たす …