The factors that allow self‐reactive B cells to escape negative selection and become
activated remain poorly defined. Using a BCR knock‐in mouse strain, we identify a pathway …

The important subtleties of B cell tolerance are best understood in a diverse immunoglobulin
(Ig) repertoire context encoding a full spectrum of autoreactivity. To achieve this, we used …

Splenectomy and Salmonella Typhi Exposure Lead to Quantitative Alterations of Bone Marrow
B220+ Cells and CD4+ T Cells on BALB/c Page 1 Turk J Immunol 2013;1(2):47-53 Turkish …

Control of B cell development through transitional stages in the periphery is critical for the
proper maintenance and selection of mature, functional B cell subsets capable of mediating …

How self-reactive B cells are regulated during naïve and antigen-driven B cell development
remains poorly understood. The peripheral B cell pro-survival cytokine B lymphocyte …

Abstract The Epstein-Barr Virus (EBV) is a gamma herpesvirus that is highly prevalent
worldwide. Primary infection with EBV typically occurs during childhood and follows a …

Non-Hodgkin's lymphoma is the fifth most common cancer in the UK, accounting for 4% of all
new cases. The control of lymphomagenesis still remains a challenge. Early growth …