[HTML][HTML] Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation

F Wolff, A Loipetzberger, W Gruber, H Esterbauer… - Oncogene, 2013 - nature.com
Imiquimod (IMQ), a nucleoside analogue of the imidazoquinoline family, is used in the
topical treatment of basal cell carcinoma (BCC) and other skin diseases. It is reported to be a …

[HTML][HTML] Hedgehog/GLI Signaling Activates Suppressor of Cytokine Signaling 1 (SOCS1) in Epidermal and Neural Tumor Cells

S Laner-Plamberger, F Wolff, A Kaser-Eichberger… - PLoS …, 2013 - journals.plos.org
Sustained hedgehog (Hh) signaling mediated by the GLI transcription factors is implicated in
many types of cancer. Identification of Hh/GLI target genes modulating the activity of other …

[HTML][HTML] Expression analysis of multiple myeloma CD138 negative progenitor cells using single molecule microarray readout

J Jacak, H Schnidar, L Muresan, G Regl… - Journal of …, 2013 - Elsevier
We present a highly sensitive bioanalytical microarray assay that enables the analysis of
small genomic sample material. By combining an optimized cDNA purification step with …