Proteins are not monolithic entities; rather, they can contain multiple domains that mediate
distinct interactions, and their functionality can be regulated through post-translational …

The histone H2A variant H2A. Z is essential for embryonic development and for proper
control of developmental gene expression programs in embryonic stem cells (ESCs) …

Morphological and functional changes of cells are important for adapting to environmental
changes and associated with continuous regulation of gene expressions. Genes are …

Oocyte-specific histone variants have been expected to play significant roles in early
embryonic development, but the exact evidence and the biological function have remained …

The incorporation of histone variants into nucleosomes is a critical mechanism for regulating
essential DNA-templated processes and for establishing distinct chromatin architectures …

DNA in the eukaryotic cell is packaged into a structure called chromatin. Chromatin is a
dynamic structure that regulates access to DNA in response to environmental stimuli. Two …

Inside the nucleus, eukaryotic DNA is organized into a highly condensed structure, which is
composed of nucleosomes as a basic structural unit and various associated non-histone …

Physical and genetic interactions involving the nonhomologous end-joining factor XLF/Nej1 Page
1 University of Calgary PRISM Repository https://prism.ucalgary.ca The Vault Open Theses and …