DNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during …

The impact of early physical and social environments on life-long phenotypes is well known.
Moreover, we have documented evidence for gene–environment interactions where …

SUMMARY DNA methylation is a widely conserved epigenetic modification. The analysis of
genome-scale DNA methylation patterns in various organisms suggests that major features …

Nanomaterials and nanotechnology have attracted more and more attention due to their
wide ranges of applications in various fields. With a high level of surface energy, high …

The molecular complex consisting of DNA and its associated proteins is referred to as
chromatin. In the central nervous system (CNS), dynamic chromatin remodelling is required …

DNA methylation is a reversible and inheritable chemical modification which involves the
addition of a methyl group to DNA catalyzed by DNA methyltransferases (DNMTs), resulting …

Accumulating evidence suggest that pluripotency–the ability to generate all somatic cell
types–is not a fixed state. Pluripotent cell populations encompass a heterogeneous group of …

Following the conclusion from chapter 3, that LSH may function in DNA methylation and
gene expression regulation as early as in the pre-implantation embryo, some other evidence …

The genetic basis of psychiatric illness is relatively undisputed, but inconsistencies such as
reduced penetrance in families and the rates of discordance in identical twins indicate that …

Résumé Il apparait de plus en plus que les miARNs ont un rôle important dans la régulation
de nombreux processus biologiques cellulaires. Cependant les mécanismes régulant leur …