Nanotechnology for tissue engineering: need, techniques and applications
Tissue engineering is very fast growing scientific area in this era which is used to create,
repair, and/or replace cells, tissues and organs by using cell and/or combinations of cells …
repair, and/or replace cells, tissues and organs by using cell and/or combinations of cells …
The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells
J Dahlmann, G Kensah, H Kempf, D Skvorc, A Gawol… - Biomaterials, 2013 - Elsevier
In most pluripotent stem cell differentiation protocols the formation of embryoid bodies (EBs)
is an important step. Here we describe a rapid, straightforward soft lithography approach for …
is an important step. Here we describe a rapid, straightforward soft lithography approach for …
A triggered DNA hydrogel cover to envelop and release single cells.
We develop an enzyme-triggered permeable DNA hydrogel cover to envelop and release
single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and …
single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and …
Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model
Intrinsic drug resistance of pancreatic ductal adenocarcinoma (PDAC) warrants studies
using models that are more clinically relevant for identifying novel resistance mechanisms …
using models that are more clinically relevant for identifying novel resistance mechanisms …
Workshop meeting report Organs-on-Chips: human disease models
A van de Stolpe, J den Toonder - Lab on a chip, 2013 - pubs.rsc.org
The concept of “Organs-on-Chips” has recently evolved and has been described as 3D (mini-
) organs or tissues consisting of multiple and different cell types interacting with each other …
) organs or tissues consisting of multiple and different cell types interacting with each other …
Alginate gel microwell arrays using electrodeposition for three-dimensional cell culture
In this study, we developed a novel method for fabricating microwell arrays constructed from
alginate gels, and the alginate gel microwells were used for three-dimensional (3D) cell …
alginate gels, and the alginate gel microwells were used for three-dimensional (3D) cell …
A strategy for the construction of controlled, three‐dimensional, multilayered, tissue‐like structures
P Gong, W Zheng, Z Huang, W Zhang… - Advanced Functional …, 2013 - Wiley Online Library
Differentiated cells make up tissues and organs, and communicate within a complex, three
dimensional (3D) environment. The spatial arrangement of cellular interactions is difficult to …
dimensional (3D) environment. The spatial arrangement of cellular interactions is difficult to …
Microwell fabrication methods and applications for cellular studies
SH Kim, GH Lee, JY Park - Biomedical Engineering Letters, 2013 - Springer
Traditional cell culture methods allow bulk biomolecular assays; however, individual cell
responses are blended, lost, and ignored. To overcome such limitations of the traditional cell …
responses are blended, lost, and ignored. To overcome such limitations of the traditional cell …
Constructing stem cell microenvironments using bioengineering approaches
DA Brafman - Physiological genomics, 2013 - journals.physiology.org
Within the adult organism, stem cells reside in defined anatomical microenvironments called
niches. These architecturally diverse microenvironments serve to balance stem cell self …
niches. These architecturally diverse microenvironments serve to balance stem cell self …