Structural implications for selective targeting of PARPs

JD Steffen, JR Brody, RS Armen, JM Pascal - Frontiers in oncology, 2013 - frontiersin.org
Poly (ADP-ribose) polymerases (PARPs) are a family of enzymes that use NAD+ as a
substrate to synthesize polymers of ADP-ribose (PAR) as post-translational modifications of …

[PDF][PDF] Global and site-specific characterization of the SUMO proteome by mass spectrometry

IA Hendriks - Mol. Cell, 2013 - scholarlypublications …
Small Ubiquitin-Like Modifier (SUMO) has been established as a post-translational
modification (PTM) of paramount importance to all eukaryotic life [1, 2]. As reviewed in the …