[HTML][HTML] STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model

L Couronné, L Scourzic, C Pilati, V Della Valle… - …, 2013 - ncbi.nlm.nih.gov
STAT3 protein phosphorylation is a frequent event in various hematologic malignancies and
solid tumors. Acquired STAT3 mutations have been recently identified in 40% of patients …

[HTML][HTML] Terminal platelet production is regulated by von Willebrand factor

S Poirault-Chassac, KA Nguyen, A Pietrzyk, C Casari… - PLoS …, 2013 - journals.plos.org
It is established that proplatelets are formed from mature megakaryocytes (MK) as
intermediates before platelet production. Recently, the presence of proplatelets was …

Aberrant expression of signaling proteins in essential thrombocythemia

W Hui, F Ye, W Zhang, C Liu, M Cui, W Li, J Xu… - Annals of …, 2013 - Springer
Dysregulated expression of signaling proteins may contribute to the pathophysiology of
essential thrombocythemia (ET). This study aimed to characterize protein expression in ET …

JAK2V617F-positive Myeloproliferative Neoplasms: KI mouse models, interferon-α therapy and clonal architecture

S Hasan - 2013 - theses.hal.science
This work concerns malignant myeloid hemopathies called classical BCR-ABL-negative
Myeloproliferative Neoplasms (MPN) and include Polycythemia Vera (PV), Essential …