The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review
K Michalakis, G Mintziori, A Kaprara, BC Tarlatzis… - Metabolism, 2013 - Elsevier
The aim of this narrative review is to provide current evidence for the interaction between
obesity, metabolic syndrome (MS) and reproductive axis. Gonadotropin-releasing hormone …
obesity, metabolic syndrome (MS) and reproductive axis. Gonadotropin-releasing hormone …
[HTML][HTML] The role of leptin in the control of insulin-glucose axis
M Amitani, A Asakawa, H Amitani, A Inui - Frontiers in neuroscience, 2013 - frontiersin.org
Obesity and diabetes mellitus are great public health concerns throughout the world
because of their increasing incidence and prevalence. Leptin, the adipocyte hormone, is …
because of their increasing incidence and prevalence. Leptin, the adipocyte hormone, is …
Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals
HS Moon, M Dalamaga, SY Kim, SA Polyzos… - Endocrine …, 2013 - academic.oup.com
Leptin is an adipocyte-secreted hormone that has been proposed to regulate energy
homeostasis as well as metabolic, reproductive, neuroendocrine, and immune functions. In …
homeostasis as well as metabolic, reproductive, neuroendocrine, and immune functions. In …
[HTML][HTML] Leptin at the intersection of neuroendocrinology and metabolism: current evidence and therapeutic perspectives
M Dalamaga, SH Chou, K Shields, P Papageorgiou… - Cell metabolism, 2013 - cell.com
Since its discovery as an adipocyte-secreted hormone, leptin has been found to impact food
intake, energy homeostasis, and metabolism through its effects on the central nervous …
intake, energy homeostasis, and metabolism through its effects on the central nervous …
Selective leptin resistance revisited
AL Mark - … Journal of Physiology-Regulatory, Integrative and …, 2013 - journals.physiology.org
In addition to effects on appetite and metabolism, leptin influences many neuroendocrine
and physiological systems, including the sympathetic nervous system. Building on my Carl …
and physiological systems, including the sympathetic nervous system. Building on my Carl …
Molecular mechanisms of central leptin resistance in obesity
CH Jung, MS Kim - Archives of pharmacal research, 2013 - Springer
The rapidly increasing prevalence of obesity confers a huge health burden globally. The
hypothalamus plays a central role in the regulation of energy homeostasis by integrating …
hypothalamus plays a central role in the regulation of energy homeostasis by integrating …
Randomized double‐blind placebo‐controlled study of leptin administration after gastric bypass
J Korner, R Conroy, G Febres, D J. McMahon… - …, 2013 - Wiley Online Library
Objective: Obese individuals have high levels of circulating leptin and are resistant to the
weight‐reducing effect of leptin administration at physiological doses. Although Roux‐en‐Y …
weight‐reducing effect of leptin administration at physiological doses. Although Roux‐en‐Y …
The role of leptin in obesity and the potential for leptin replacement therapy
H Feng, L Zheng, Z Feng, Y Zhao, N Zhang - Endocrine, 2013 - Springer
Leptin (from the Greek word “lepto''meaning “thin”) is a 167-amino acid peptide hormone
encoded by the obesity (ob) gene and secreted by white adipocytes. Blood leptin …
encoded by the obesity (ob) gene and secreted by white adipocytes. Blood leptin …
Kisspeptin as a link between metabolism and reproduction: evidences from rodent and primate studies
Changes in metabolic status gate reproductive activity by still incompletely deciphered
mechanisms. Many neuropeptides have been shown to be involved in restraining …
mechanisms. Many neuropeptides have been shown to be involved in restraining …